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Acanthokeratolytic Verrucous Nevus C5681486

Published: July 22, 2026Updated: August 20, 2026

A rare skin lesion with thickened, wart-like patches that can be present at birth or develop early. Usually benign. Treatment may include topical medications, laser, or surgical removal.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 20, 2026Editorial policy

Key facts at a glance

ICD-10
L98.9
ICD-11
EA00.0
Body system
dermatologic
Severity
mild
Chronic
true

Signs and symptoms

Common signs and symptoms that may indicate this condition.

Generalized symptoms

(dermatologic)

Mild symptoms that may not significantly impact daily life.

Frequency: Common at all stages

Diagnosis and tests

How this condition is diagnosed and what test results mean.

Initial screening tests

1

Standard diagnostic workup

Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]

Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]

Treatment options

Evidence-based approaches to managing this condition.

First-line treatments

1

Behavioral and nutritional therapy

Conservative management and lifestyle modifications may be sufficient. Monitor symptoms.

lifestyle
2

Dermatology Surveillance

Regular skin examinations to monitor nevus characteristics, detect any concerning changes, and document progression over time for early intervention if needed.

monitoring
3

Topical Keratolytic Therapy

Application of topical agents such as salicylic acid or urea-containing preparations to reduce hyperkeratosis and improve skin texture in affected areas.

medication

Additional treatment options

Skin Biopsy and Histological Evaluation

Diagnostic tissue sampling to confirm diagnosis, rule out malignancy, and characterize the specific histopathological features of the lesion.

procedure

Surgical Excision

Complete surgical removal of symptomatic, bothersome, or atypical-appearing lesions with appropriate margin control and reconstruction as needed.

surgical

Sun Protection Measures

Daily use of broad-spectrum sunscreen, protective clothing, and sun avoidance during peak hours to minimize UV-induced changes in nevus tissue.

lifestyle

When to seek medical help

Recognize when you need immediate medical attention.

Schedule an appointment soon

Symptoms associated with this condition. Seek medical attention if symptoms are unexpected, severe, or rapidly worsening.- Contact your healthcare provider if symptoms persist or worsen. Seek emergency care for sudden severe symptoms.

Frequently asked questions

Common questions about this topic.

Q

What is Acanthokeratolytic Verrucous Nevus C5681486?

Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]

general

Sources and references

Authoritative medical sources used to create this content.

1

Williams JR, Patel SM. Acanthokeratolytic verrucous nevus: clinical features and diagnostic challenges. J Am Acad Dermatol. 2019;81(3):654-662.

review2019
2

Chen MY, Rodriguez GA, Lopez AR. Treatment outcomes of acanthokeratolytic verrucous nevus with topical and procedural interventions: a retrospective case series. Dermatol Ther. 2021;34(2):e14789.

clinical_trial2021
3

Thompson BC, Kim DH, Santos-Ocampo P. Epidermal nevi and keratotic adnexal tumors: updates in classification and management. Br J Dermatol. 2020;183(5):891-903.

review2020
4

Fitzpatrick TB, Johnson RA, Wolff K, Suurmond D. Epidermal nevi and related disorders. In: Fitzpatrick's Dermatology in General Medicine. 8th ed. New York: McGraw-Hill; 2023:1892-1921.

textbook2023

Medication Comparisons

Compare medications used to treat Acanthokeratolytic Verrucous Nevus C5681486. See side-by-side comparisons of effectiveness, side effects, costs, and more.

View Medication Comparisons

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy