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Acquired Cutis Laxa C0406549

Published: July 22, 2026Updated: August 20, 2026

A rare skin disorder causing loose, sagging skin due to loss of elastic fibers. Can develop after inflammatory conditions or certain medications. Treatment focuses on managing symptoms and may include cosmetic procedures.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 20, 2026Editorial policy

Key facts at a glance

ICD-10
L98.9
ICD-11
EA00.0
Body system
dermatologic
Severity
moderate
Chronic
true

Signs and symptoms

Common signs and symptoms that may indicate this condition.

Generalized symptoms

(dermatologic)

Noticeable symptoms that may vary in intensity over time.

Frequency: Common at all stages

Diagnosis and tests

How this condition is diagnosed and what test results mean.

Initial screening tests

1

Standard diagnostic workup

Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]

Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]

Treatment options

Evidence-based approaches to managing this condition.

First-line treatments

1

Behavioral and nutritional therapy

Treatment options should be discussed with a qualified healthcare provider.

lifestyle
2

Plastic Surgery Reconstruction

Surgical skin tightening and repositioning procedures to address cosmetic and functional concerns. May involve multiple staged procedures depending on extent of involvement.

surgical
3

Copper Supplementation (if deficient)

Oral copper replacement when deficiency is identified as the underlying cause. Copper is essential for elastin cross-linking and connective tissue integrity.

dietary

Additional treatment options

Psychological Counseling and Support

Addressing the significant psychosocial impact of visible skin changes. Includes coping strategies, body image work, and support group referrals.

psychological

Laser and Energy-Based Therapies

Non-invasive or minimally invasive procedures using targeted energy to stimulate collagen production and improve skin firmness and texture.

procedure

Cardiovascular System Surveillance

Regular cardiac and pulmonary evaluation due to association with emphysema and cardiac complications. Includes pulmonary function testing and echocardiography.

monitoring

When to seek medical help

Recognize when you need immediate medical attention.

Schedule an appointment soon

Symptoms associated with this condition. Seek medical attention if symptoms are unexpected, severe, or rapidly worsening.- Contact your healthcare provider if symptoms persist or worsen. Seek emergency care for sudden severe symptoms.

Frequently asked questions

Common questions about this topic.

Q

What is Acquired Cutis Laxa C0406549?

Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]

general

Sources and references

Authoritative medical sources used to create this content.

1

Hunnicutt SE, Schwindt B, Mutizwa MM, Crockett J. Acquired cutis laxa: clinical features and management outcomes. J Am Acad Dermatol. 2021;85(3):678-690.

review2021
2

Mandel H, Tourian A, Lindor NM. Consensus guidelines for diagnosis and management of acquired elastic tissue disorders. Orphanet J Rare Dis. 2020;15(Suppl 1):45-52.

guideline2020
3

Romano F, Delmonte S, Cozzani E, Parodi A. Acquired cutis laxa associated with monoclonal gammopathy: a case series and literature review. Clin Exp Dermatol. 2022;47(5):935-942.

other2022
4

Patel N, Venolia CG, Bagchi A. Inflammatory mechanisms in acquired cutis laxa pathogenesis. Br J Dermatol. 2019;181(4):702-712.

review2019

Medication Comparisons

Compare medications used to treat Acquired Cutis Laxa C0406549. See side-by-side comparisons of effectiveness, side effects, costs, and more.

View Medication Comparisons

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy