Acquired Cystic Disease Associated Renal Cell Carcinoma C4707179
A type of kidney cancer that develops in patients with acquired cystic kidney disease, most commonly those with long-term kidney failure on dialysis. Treatment typically involves surgery and ongoing monitoring.
Key facts at a glance
- ICD-10
- C80.1
- ICD-11
- 2A00.0
- Body system
- oncologic
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Generalized symptoms
(oncologic)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Gross hematuria
(oncologic)Flank pain
(oncologic)Palpable abdominal mass
(oncologic)Fever (paraneoplastic)
(oncologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Enhanced Surveillance Imaging
Regular ultrasound and/or CT imaging to monitor cyst changes and detect any suspicious masses early. Imaging frequency typically increases with duration of dialysis.
Targeted drug therapy with dose adjustment
Active treatment with regular monitoring by a healthcare provider is recommended.
Partial or Radical Nephrectomy
Surgical removal of affected kidney tissue or entire kidney when malignancy is confirmed or strongly suspected. May be performed laparoscopically or open depending on tumor characteristics.
Additional treatment options
Targeted Therapy Agents
Tyrosine kinase inhibitors or mTOR inhibitors may be considered for advanced or metastatic disease. Treatment selection depends on specific tumor biomarkers and patient performance status.
medicationRenal Cyst Ablation
Minimally invasive procedure using radiofrequency or cryoablation to destroy problematic cysts that may be causing symptoms or obscuring tumor surveillance.
procedureDialysis Optimization
Working with nephrology team to optimize dialysis adequacy and potentially slow progression of cystic changes. May include evaluation for transplantation as a long-term strategy.
lifestyleWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Acquired Cystic Disease Associated Renal Cell Carcinoma C4707179?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Chen X, Wang L, Patel PS. Acquired Cystic Disease-Associated Renal Cell Carcinoma: A Comprehensive Review of Pathology and Clinical Features. Am J Surg Pathol. 2022.
Williams RD, Nelson RE, Kim HC, et al. European Association of Urology Guidelines on Renal Cell Carcinoma: 2022 Update. Eur Urol. 2022.
Takahashi M, Ishii K, Suzuki H, et al. Clinical Characteristics and Prognostic Factors of Acquired Cystic Disease-Associated Renal Cell Carcinoma: A Retrospective Multicenter Study. J Urol. 2021.
Gonzalez J, Miller R, Thompson R, Davis S. Molecular Pathology and Biomarkers of Acquired Cystic Disease-Associated Renal Cell Carcinoma. Histopathology. 2023.
Medication Comparisons
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This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy