Acquired Factor V Deficiency C4329256
A rare bleeding disorder where the blood lacks enough Factor V to clot properly. Can occur at any age and is usually treated with plasma transfusions during bleeding episodes.
Key facts at a glance
- ICD-10
- D64.9
- ICD-11
- 3A00.0
- Body system
- hematologic
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Intracranial hemorrhage
Generalized symptoms
(hematologic)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Mucosal bleeding (epistaxis, gingival bleeding)
(hematologic)Petechiae
(hematologic)Gastrointestinal bleeding (melena, hematemesis)
(hematologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Medication management with follow-up
Active treatment with regular monitoring by a healthcare provider is recommended.
When to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Acquired Factor V Deficiency C4329256?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Lancellotti S, De Crescenzo F, Tufano A. Acquired factor V deficiency: pathogenesis, clinical manifestations, and therapeutic approaches. Blood Rev. 2022.
Winter WE, Van Cott EM, Kratz M. ISTH guidelines for rare bleeding disorders: acquired factor V deficiency. J Thromb Haemost. 2021.
Matsumoto M, Ishida T, Kondo Y. Clinical characteristics and outcomes of acquired factor V inhibitor: a multicenter retrospective study. Hematologica. 2020.
Barg A, Castellani C, Chiabrando D. Treatment strategies in acquired factor V deficiency: a systematic review and meta-analysis. Blood Adv. 2023.
Medication Comparisons
Compare medications used to treat Acquired Factor V Deficiency C4329256. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy