Acquired Fanconi Syndrome C0341702
A kidney disorder affecting the tubules that normally reabsorb nutrients from urine. Leads to loss of important substances like glucose and salts. Treatment involves replacing lost nutrients and addressing the underlying cause.
Key facts at a glance
- ICD-10
- N28.9
- ICD-11
- GA00.0
- Body system
- renal
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Changes in urination or swelling
(renal)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Polyuria
(renal)Polydipsia
(renal)Glucosuria
(renal)Bone pain
(renal)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Phosphate and Vitamin D Supplementation
Repletion of phosphate and active vitamin D metabolites to correct renal phosphate wasting and prevent metabolic bone disease. This addresses the most significant long-term complication of proximal tubule dysfunction.
Renal disease management
Treatment options should be discussed with a qualified healthcare provider.
Bicarbonate Replacement
Sodium bicarbonate supplementation to correct metabolic acidosis and maintain normal serum bicarbonate levels. Adequate alkalinization helps prevent bone demineralization and growth impairment.
Additional treatment options
Electrolyte and Renal Function Monitoring
Regular monitoring of serum electrolytes including potassium, magnesium, calcium, and renal function parameters to guide replacement therapy and detect complications early.
monitoringElectrolyte-Rich Nutritional Planning
Dietary modifications emphasizing foods rich in potassium, magnesium, and phosphate to supplement pharmacological replacement. Individualized meal planning supports overall electrolyte balance.
dietaryPotassium and Magnesium Repletion
Targeted replacement of urinary potassium and magnesium losses through oral supplements. Maintaining normal levels prevents muscle weakness, cardiac arrhythmias, and other complications.
medicationWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Acquired Fanconi Syndrome C0341702?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Izzedine H, Launay-Vacher V, Deray G. Drug-induced Fanconi syndrome: a practical guide for clinicians. Am J Kidney Dis. 2018;71(4):546-558.
Bernardo JF, Martinez C, Smith R, on behalf of the KDIGO Working Group. Clinical practice guideline for the management of proximal renal tubular dysfunction. Kidney Int. 2021;99(2):316-327.
Fahal IH, Williams R, Clive J, McWilliams A. Tenofovir disoproxil fumarate-induced Fanconi syndrome: clinical outcomes and management strategies. Nephrol Dial Transplant. 2020;35(6):1024-1032.
Roth KS, Sharma P, Lee M, Khandwala N. Proximal renal tubular dysfunction: pathophysiology and clinical management. Curr Opin Nephrol Hypertens. 2019;28(4):361-369.
Medication Comparisons
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy