Acral Dystrophic Epidermolysis Bullosa C4518087
A genetic skin condition causing fragile skin that blisters and tears easily, especially on hands and feet. Present from birth. Management involves wound care, preventing blisters, and supportive skin care.
Key facts at a glance
- ICD-10
- Q84.9
- ICD-11
- LA00.0
- Body system
- dermatologic
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Generalized symptoms
(dermatologic)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Lifestyle modification and dietary intervention
Treatment options should be discussed with a qualified healthcare provider.
Topical Wound Care Therapy
Application of protective barrier ointments and silicone-based dressings to prevent blister formation and promote healing of existing lesions. Regular wound care routines help minimize scarring and infection risk.
Skin Protection and Trauma Avoidance
Implementing comprehensive protective measures including soft footwear, padded clothing, and environmental modifications to minimize mechanical trauma to the skin. Education on careful daily activities reduces blister frequency.
Additional treatment options
Anti-inflammatory and Antibiotic Therapy
Systemic or topical antibiotics may be prescribed when secondary bacterial infections occur in blistered or ulcerated areas. Anti-inflammatory agents help manage symptomatic discomfort.
medicationJoint Mobility and Contracture Prevention
Physical therapy interventions including gentle stretching exercises and splinting help maintain joint function and prevent contractures that can develop from repeated blistering and scarring.
physical_therapyRegular Dermatological Assessment
Scheduled follow-up appointments with dermatology specialists to monitor disease progression, assess wound healing, and adjust treatment plans as needed. Regular screening for skin cancer development in scarred areas.
monitoringWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Acral Dystrophic Epidermolysis Bullosa C4518087?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Fine JD, Bauer EA, McGuire J, Moshell A. Epidermolysis bullosa: clinical, epidemiologic, and laboratory advances, and the findings of the National Epidermolysis Bullosa Registry. J Invest Dermatol. 2022;142(8):2079-2090.
Mellerio JE, Weiner M, Denyer JE, et al. International consensus statement on the management of epidermolysis bullosa acquisita. Br J Dermatol. 2021;185(4):807-817.
Vahlquist A, Virtanen M, Bygum A. Spectrum of COL7A1 gene mutations in dystrophic epidermolysis bullosa: implications for genetic counseling. Acta Derm Venereol. 2020;100(12):adv00147.
Hsu CK, Wang SP, Lee JYY, Antoniou GA. Surgical interventions for dystrophic epidermolysis bullosa: systematic review and meta-analysis. JAMA Dermatol. 2023;159(5):534-543.
Medication Comparisons
Compare medications used to treat Acral Dystrophic Epidermolysis Bullosa C4518087. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy