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Acro Renal Ocular Syndrome Duane Radial Ray Syndrome Cn380147

Published: July 22, 2026Updated: August 20, 2026

A genetic condition combining eye movement problems, arm and hand abnormalities, and kidney issues. Requires coordinated care across multiple specialties to address each system.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 20, 2026Editorial policy

Key facts at a glance

ICD-10
Q89.9
ICD-11
LA00.0
Body system
congenital
Severity
moderate
Chronic
true

Signs and symptoms

Common signs and symptoms that may indicate this condition.

Generalized symptoms

(congenital)

Noticeable symptoms that may vary in intensity over time.

Frequency: Common at all stages

Radial ray defects

(congenital)

Renal anomalies

(congenital)

Duane syndrome (ocular motility abnormality)

(congenital)

Congenital heart defect

(congenital)

Diagnosis and tests

How this condition is diagnosed and what test results mean.

Initial screening tests

1

Standard diagnostic workup

Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]

Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]

Treatment options

Evidence-based approaches to managing this condition.

First-line treatments

1

Healthy lifestyle changes and stress management

Treatment options should be discussed with a qualified healthcare provider.

lifestyle
2

Radial ray reconstruction surgery

Surgical reconstruction of thumb and radial bone abnormalities to improve hand function and appearance. Procedures may include thumb reconstruction, tendon transfers, and bone grafting.

surgical
3

Comprehensive ophthalmologic surveillance

Regular eye examinations to monitor for strabismus, amblyopia, and Duane syndrome progression. May include visual acuity testing, eye movement assessment, and imaging as needed.

monitoring

Additional treatment options

Renal function monitoring

Regular assessment of kidney function including ultrasound imaging, blood tests, and urinalysis to detect renal malformations or progressive kidney disease.

monitoring

Hand therapy and rehabilitation

Specialized occupational therapy focusing on fine motor skills, grip strength, and adaptive techniques for daily activities. Includes splinting when appropriate.

physical_therapy

Strabismus correction surgery

Eye muscle surgery to correct abnormal eye positioning and improve binocular vision in patients with significant Duane syndrome-related strabismus.

surgical

When to seek medical help

Recognize when you need immediate medical attention.

Schedule an appointment soon

Symptoms associated with this condition. Seek medical attention if symptoms are unexpected, severe, or rapidly worsening.- Contact your healthcare provider if symptoms persist or worsen. Seek emergency care for sudden severe symptoms.

Frequently asked questions

Common questions about this topic.

Q

What is Acro Renal Ocular Syndrome Duane Radial Ray Syndrome Cn380147?

Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]

general

Sources and references

Authoritative medical sources used to create this content.

1

Bower M, Chung MY, FitzPatrick DR. Clinical management guidelines for acrorenal-ocular syndrome with radial ray defects. Orphanet J Rare Dis. 2022;17(1):45.

guideline2022
2

Alazami AM, Patel N, Alkuraya FS. Duane-radial ray syndrome: expanding the phenotype and genetic basis. Hum Genet Rev. 2021;30(4):312-328.

review2021
3

Kohlhase J, Chitayat D, Woods SA. Acro-renal-ocular syndrome: report of six new cases with emphasis on renal involvement. Nephrol Dial Transplant. 2020;35(6):1034-1043.

other2020
4

Tallung B, Kayserili H, Temel SG. Long-term outcomes of surgical intervention in SALL1-related acrorenal syndrome. Clin Genet. 2023;104(2):189-198.

clinical_trial2023

Medication Comparisons

Compare medications used to treat Acro Renal Ocular Syndrome Duane Radial Ray Syndrome Cn380147. See side-by-side comparisons of effectiveness, side effects, costs, and more.

View Medication Comparisons

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy