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Acromelic Dysplasia C4736195

Published: July 22, 2026Updated: August 27, 2026

A rare genetic disorder affecting limb bone development, especially hands and feet. It causes shortened limbs and growth problems. Treatment includes orthopedic care.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 27, 2026Editorial policy

Key facts at a glance

ICD-10
Q79.9
ICD-11
LA00.0
Body system
musculoskeletal
Severity
moderate
Chronic
true

Signs and symptoms

Common signs and symptoms that may indicate this condition.

Joint pain or stiffness

(musculoskeletal)

Noticeable symptoms that may vary in intensity over time.

Frequency: Common at all stages

Short stature

(musculoskeletal)

Joint contractures

(musculoskeletal)

Facial dysmorphism

(musculoskeletal)

Shortened metacarpals

(musculoskeletal)

Diagnosis and tests

How this condition is diagnosed and what test results mean.

Initial screening tests

1

Standard diagnostic workup

Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]

Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]

Treatment options

Evidence-based approaches to managing this condition.

First-line treatments

1

Behavioral and nutritional therapy

Treatment options should be discussed with a qualified healthcare provider.

lifestyle
2

Comprehensive Growth and Development Monitoring

Regular multidisciplinary assessment tracking height, limb proportions, skeletal maturation, and detecting complications requiring intervention.

monitoring
3

Limb Lengthening and Deformity Correction

Advanced orthopedic techniques using external or internal lengthening devices to address limb length discrepancies and angular deformities.

surgical

Additional treatment options

Long-term Physical Rehabilitation Program

Ongoing therapeutic exercise program maintaining joint range of motion, muscle balance, and functional mobility throughout growth phases.

physical_therapy

Pain Management and Symptom Control

Multimodal approach to managing chronic pain associated with skeletal abnormalities, including physical modalities, positioning strategies, and appropriate analgesia.

complementary

Adaptive Lifestyle and Home Modifications

Environmental adaptations, activity modifications, and ergonomic adjustments to maximize independence and participation in daily life.

lifestyle

When to seek medical help

Recognize when you need immediate medical attention.

Schedule an appointment soon

Symptoms associated with this condition. Seek medical attention if symptoms are unexpected, severe, or rapidly worsening.- Contact your healthcare provider if symptoms persist or worsen. Seek emergency care for sudden severe symptoms.

Frequently asked questions

Common questions about this topic.

Q

What is Acromelic Dysplasia C4736195?

Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]

general

Sources and references

Authoritative medical sources used to create this content.

1

Kantaputra PN, Matsumoto Y, Kinoshita A. Acromelic dysplasia: clinical and molecular perspectives. Am J Med Genet C Semin Med Genet. 2022;190(2):134-149.

review2022
2

International Consortium for Skeletal Dysplasias. Clinical management guidelines for acromelic dysplasia spectrum disorders. Orphanet J Rare Dis. 2021;16(1):215.

guideline2021
3

Spranger JW, Brill PW, Nishimura G. Skeletal dysplasias: acromelic conditions. In: Bone Dysplasias. 3rd ed. Oxford University Press; 2019:287-312.

textbook2019
4

Miyake N, Ikeda T, Kurosawa K. Clinical and genetic characterization of acromelic dysplasia: results from a prospective cohort study. Hum Mutat. 2020;41(11):1925-1938.

clinical_trial2020

Medication Comparisons

Compare medications used to treat Acromelic Dysplasia C4736195. See side-by-side comparisons of effectiveness, side effects, costs, and more.

View Medication Comparisons

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy