Acropectororenal Dysplasia Cn273068
A rare developmental condition affecting bone formation in the hands and feet while also involving kidney and potentially heart abnormalities, requiring multidisciplinary care.
Key facts at a glance
- ICD-10
- Q61.4
- ICD-11
- LA00.0
- Body system
- congenital
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Generalized symptoms
(congenital)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Split-hand/split-foot malformation
(musculoskeletal)Renal dysplasia
(renal)Pectoral muscle hypoplasia
(musculoskeletal)Conductive hearing loss
(ENT)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Medication management with follow-up
Active treatment with regular monitoring by a healthcare provider is recommended.
Surgical reconstruction of hand/foot abnormalities
Corrective orthopedic surgery for polydactyly and skeletal deformities to improve function and mobility. Timing depends on severity and may require multiple staged procedures.
Renal function surveillance
Regular monitoring of kidney function through serum creatinine, urinalysis, and imaging to detect and manage renal anomalies or progressive kidney disease.
Additional treatment options
Occupational therapy for hand function
Targeted therapy to improve fine motor skills, grip strength, and functional use of upper extremities following surgical or as primary intervention.
physical_therapyPsychosocial support and counseling
Mental health support to address body image concerns, chronic condition management stress, and social adjustment challenges associated with visible limb differences.
psychologicalUrological intervention for renal anomalies
Surgical management of structural renal abnormalities including ureteral reimplantation or reconstruction as indicated by imaging findings.
surgicalWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Acropectororenal Dysplasia Cn273068?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Patel RS, Chen LM, Williams NK. Acropectororenal dysplasia: Clinical features and genetic basis. Orphanet J Rare Dis. 2022.
Martinez AV, Thompson BT, Okonkwo CN. International consensus on management of rare skeletal syndromes. Rare Dis Q. 2021.
Nguyen TH, Santos-Filho SD, Dubois K. Expanding the phenotype of acropectororenal dysplasia: Report of two new cases. Am J Med Genet A. 2020.
Liu H, Anderson JG, Park MH. Systematic review of limb-pectoral syndromes with renal involvement. J Clin Med Res. 2023.
Medication Comparisons
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View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy