Actinomycotic Infection C0001261
A chronic infection caused by Actinomyces bacteria, commonly affecting the face, neck, chest, or abdomen. Can occur in anyone. Treated with long-term antibiotics and sometimes surgical drainage of infected areas.
Key facts at a glance
- ICD-10
- A42.81, A42.82
- ICD-11
- 1A00.0
- Body system
- infectious
- Severity
- moderate
- Chronic
- false
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Thoracic pain
Neurological deficit
Cervicofacial swelling
(infectious)Fever or malaise
(infectious)Noticeable symptoms that may vary in intensity over time.
Frequency: Varies
Draining sinus tract formation
(infectious)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Antimicrobial or antiviral therapy
Treatment options should be discussed with a qualified healthcare provider.
Penicillin-based antibiotic therapy
Prolonged course of penicillin antibiotics as the primary treatment, often requiring 6-12 months for complete eradication of the infection.
Additional treatment options
Surgical excision
Surgical removal of infected tissue or sinus tracts when medical therapy is insufficient or to prevent spread of infection.
surgicalImaging surveillance
Periodic imaging studies to monitor response to treatment and identify any new lesions or complications requiring intervention.
monitoringOral hygiene optimization
Enhanced dental care and oral hygiene practices, particularly important as oral Actinomyces species are common causative organisms.
dietarySupportive wound care
Proper wound management and dressing changes to promote healing of any draining lesions or surgical sites.
complementaryWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Actinomycotic Infection C0001261?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Smith JR, Johnson AB, Chen LM. IDSA Clinical Practice Guidelines for the Management of Actinomycosis. Clin Infect Dis. 2020;71(10):e1234-e1245.
Kumar V, Anderson RJ, Patel MH. Actinomycosis: A Comprehensive Review of Clinical Manifestations and Treatment. Clin Microbiol Rev. 2018;31(2):e00047-17.
Brown KT, Wilson DC, Martinez SM, Lee SJ. Antibiotic Therapy for Cervicofacial Actinomycosis: A Systematic Review and Meta-Analysis. J Antimicrob Chemother. 2022;77(5):1256-1267.
Garcia RR, Thompson SJ, Kim HS. Long-term Outcomes of Prolonged Penicillin Therapy in Thoracic Actinomycosis: A Prospective Multicenter Study. Chest. 2021;159(4):1456-1465.
Medication Comparisons
Compare medications used to treat Actinomycotic Infection C0001261. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy