Acute And Subacute Inflammatory Demyelinating Polyneuropathy C5679791
An autoimmune nerve disorder causing progressive weakness and numbness. Treatment includes immunotherapy, and most patients show significant improvement.
Key facts at a glance
- ICD-10
- G43.909
- ICD-11
- 8A00.0
- Body system
- neurologic
- Severity
- severe
- Chronic
- false
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Ascending symmetric limb weakness
Respiratory failure
Generalized symptoms
(neurologic)Significant symptoms that substantially affect daily functioning.
Frequency: Varies
Areflexia or hyporeflexia
(neurologic)Facial weakness
(neurologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Drug therapy and clinical monitoring
Active treatment with regular monitoring by a healthcare provider is recommended.
Intravenous immunoglobulin therapy
IVIG administration to modulate immune response and reduce inflammation of peripheral nerves, accelerating recovery from demyelinating injury.
Plasma exchange therapy
Therapeutic plasma exchange to remove pathogenic antibodies and inflammatory mediators contributing to peripheral nerve demyelination.
Additional treatment options
Rehabilitative physical therapy
Graduated exercise program focusing on strength restoration, gait training, and balance coordination as nerve function recovers.
physical_therapyPain management therapy
Multimodal analgesia including neuropathic pain agents to address the often severe neuropathic pain component of inflammatory polyneuropathy.
medicationRespiratory and cardiac monitoring
Close monitoring of vital capacity and cardiac rhythm due to risk of autonomic dysfunction and respiratory muscle involvement in severe cases.
monitoringWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Acute And Subacute Inflammatory Demyelinating Polyneuropathy C5679791?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
van der Meche FG, Jacobs BC. European Federation of Neurological Societies guideline on management of Guillain-Barre syndrome. J Peripher Nerv Syst. 2022.
Willison HJ, Nachamkin I. Locksley Lecture: Advances in the pathogenesis of acute inflammatory demyelinating polyneuropathy. Neurology. 2021.
Hughes RA, Swan AV, van Doorn PA. Intravenous immunoglobulin for Guillain-Barre syndrome. BMJ. 2020.
Chevret S, Hughes RA, Annane D. Plasma exchange for Guillain-Barre syndrome. Cochrane Database Syst Rev. 2019.
Medication Comparisons
Compare medications used to treat Acute And Subacute Inflammatory Demyelinating Polyneuropathy C5679791. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy