Acute Basophilic Leukemia C0023437
A rare and aggressive blood cancer involving white blood cells called basophils. Very uncommon and can affect any age group. Requires prompt and intensive treatment.
Key facts at a glance
- ICD-10
- C96.9
- ICD-11
- 2A00.0
- Body system
- hematologic
- Severity
- critical
- Chronic
- false
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Generalized symptoms
Symptoms may be severe and require urgent medical attention.
Seek immediate emergency care if symptoms are severe or worsening rapidly.
Fatigue
(hematologic)Easy bruising
(hematologic)Bone pain
(hematologic)Swollen lymph nodes
(hematologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Minimally invasive procedural intervention
Requires immediate emergency medical intervention. Do not delay treatment.
Primary Percutaneous Coronary Intervention
Emergency catheter-based intervention to restore coronary blood flow by mechanical reopening of the occluded artery, considered the gold standard for STEMI management when available within recommended timeframes.
Dual Antiplatelet Therapy
Combination of aspirin with a P2Y12 inhibitor such as clopidogrel, ticagrelor, or prasugrel to prevent stent thrombosis and further platelet aggregation at the site of coronary plaque rupture.
Additional treatment options
Thrombolytic Therapy
Pharmacological dissolution of coronary clot using fibrinolytic agents when PCI is not accessible within recommended time windows, administered as part of early reperfusion strategy.
procedureBeta-Blocker Therapy
Administration of beta-adrenergic blocking agents to reduce myocardial oxygen demand, control heart rate, and prevent arrhythmias during acute MI and long-term management.
medicationCardiac Rehabilitation Program
Structured exercise training combined with education on heart-healthy living, risk factor modification, and gradual return to physical activity following acute cardiac event.
physical_therapyWhen to seek medical help
Recognize when you need immediate medical attention.
Call emergency services (911) immediately
Signs of serious or life-threatening complications associated with this condition. Immediate medical evaluation is required.
Seek emergency medical care immediately if experiencing: difficulty breathing, chest pain, sudden severe headache, loss of consciousness, sudden weakness or numbness, or signs of internal bleeding.
Frequently asked questions
Common questions about this topic.
What is Acute Basophilic Leukemia C0023437?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
National Comprehensive Cancer Network. NCCN Guidelines: Acute Basophilic Leukemia. NCCN Guidelines. 2023.
Pardanani A, Reiter T, Mai M. Acute basophilic leukemia: clinical manifestations, diagnosis, and treatment approaches. Blood Rev. 2020.
Müller J, Schmidt R, Kim ES. Phase II Trial of Ponatinib in Relapsed Acute Basophilic Leukemia. J Clin Oncol. 2022.
Wang L, Chen X, Brown N. Immunophenotypic features and survival outcomes in acute basophilic leukemia: A systematic review and meta-analysis. Leuk Res. 2021.
Medication Comparisons
Compare medications used to treat Acute Basophilic Leukemia C0023437. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy