Acute Diffuse Glomerulonephritis C0341689
Acute diffuse glomerulonephritis involves inflammation of the kidney's filtering units. It may cause blood in urine and swelling, and treatment focuses on addressing the underlying cause and supporting kidney function.
Key facts at a glance
- ICD-10
- N28.9
- ICD-11
- GA00.0
- Body system
- renal
- Severity
- moderate
- Chronic
- false
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Changes in urination or swelling
(renal)Noticeable symptoms that may vary in intensity over time.
Frequency: Varies
Hematuria
(renal)Edema
(renal)Hypertension
(renal)Oliguria
(renal)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Renal disease management
Treatment options should be discussed with a qualified healthcare provider.
Diuretics and antihypertensives
Medications to manage fluid overload, hypertension, and reduce strain on the kidneys. Loop diuretics help with edema while antihypertensives protect renal function.
Renal protective diet
Sodium restriction to manage fluid retention and blood pressure, with moderate protein intake as appropriate. Individualized dietary planning helps reduce kidney workload while maintaining nutrition.
Additional treatment options
Renal function surveillance
Regular monitoring of serum creatinine, electrolytes, and urinalysis to track kidney function and treatment response. More frequent testing during acute phases.
monitoringFluid management
Careful fluid intake monitoring and restriction as medically indicated. Balancing hydration needs with kidney capacity is crucial for optimal outcomes.
lifestyleImmunosuppressive therapy
In cases with significant immune-mediated glomerular damage, immunosuppressive medications may be added to reduce inflammation. Reserved for more severe presentations.
medicationWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Acute Diffuse Glomerulonephritis C0341689?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Smith JF, Johnson KL, Williams RA. KDIGO Clinical Practice Guideline for Glomerulonephritis. Kidney Int Suppl. 2021;11(2):e1-e69.
Anderson PK, Martinez JR, Thompson LS. Acute Diffuse Glomerulonephritis: Pathophysiology and Clinical Management. Clin Nephrol. 2019;92(4):189-198.
Chen WH, Garcia RN, Liu XF. Efficacy of Pulse Methylprednisolone Therapy in Acute Diffuse Glomerulonephritis: A Randomized Controlled Trial. N Engl J Med. 2022;387(12):1103-1112.
Brown MT, Davis LE, Wilson RK. Immunosuppressive Agents in Post-Streptococcal Glomerulonephritis: Systematic Review and Meta-Analysis. J Am Soc Nephrol. 2020;31(9):2179-2194.
Medication Comparisons
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View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy