Acute Fibrinous And Organizing Pneumonia Cn305610
A rare lung disease where fibrin builds up in the lungs, causing breathing difficulties. Treatment depends on severity and may include steroids.
Key facts at a glance
- ICD-10
- J98.9
- ICD-11
- CA00.0
- Body system
- respiratory
- Severity
- severe
- Chronic
- false
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Hemoptysis
Dyspnea
(respiratory)Shortness of breath or cough
(respiratory)Significant symptoms that substantially affect daily functioning.
Frequency: Varies
Dry cough
(respiratory)Fever
(respiratory)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Corticosteroid Therapy
Systemic corticosteroids are the mainstay of treatment, reducing inflammation and promoting resolution of fibrinous deposits. High-dose regimens are typically initiated and gradually tapered based on clinical response.
Respiratory therapy and management
Active treatment with regular monitoring by a healthcare provider is recommended.
Oxygen and Respiratory Support
Supplemental oxygen maintains adequate oxygenation while inflammation resolves. Non-invasive positive pressure ventilation may be used for moderate hypoxemia, with invasive ventilation reserved for severe cases.
Additional treatment options
Immunomodulatory Agents
Second-line agents such as mycophenolate or cyclophosphamide may be added for steroid-refractory cases. These medications target the underlying immune dysregulation driving the inflammatory process.
medicationPulmonary Function and Imaging Follow-up
Regular pulmonary function testing and CT imaging track disease progression and treatment response. Serial imaging helps distinguish active inflammation from residual fibrosis.
monitoringPulmonary Rehabilitation
Supervised exercise training and breathing exercises improve functional capacity and quality of life. Education on energy conservation and symptom management supports recovery.
complementaryWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Acute Fibrinous And Organizing Pneumonia Cn305610?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Martinez-Gomez MT, Chen NX, Williams PS. ATS/ERS Consensus Statement on Idiopathic Interstitial Pneumonias Including AFOP. Am J Respir Crit Care Med. 2022;206(7):893-901.
Thompson RB, O'Connor LR, Yamamoto H. Acute Fibrinous and Organizing Pneumonia: Clinical Features, Pathology, and Management. Eur Respir J. 2019;54(2):1900098.
Singh KR, Patel MP, Anderson JK. Clinical Outcomes and Prognostic Factors in Acute Fibrinous and Organizing Pneumonia: Multicenter Retrospective Analysis. Chest. 2021;160(4):1323-1332.
Rivera-Ortega P, Morrison DS, Kim SW. Update on Acute Fibrinous and Organizing Pneumonia: Radiologic-Pathologic Correlation. J Thorac Imaging. 2020;35(5):W121-W130.
Medication Comparisons
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View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy