Acute Inflammatory Demyelinating Polyradiculoneuropathy C4551910
An autoimmune condition where the body attacks nerve coverings, causing weakness and numbness. Often follows an infection and is treated with immunotherapy.
Key facts at a glance
- ICD-10
- G43.909
- ICD-11
- 8A00.0
- Body system
- neurologic
- Severity
- severe
- Chronic
- false
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Ascending symmetric weakness
Areflexia
Facial weakness
Respiratory failure requiring mechanical ventilation
Generalized symptoms
(neurologic)Significant symptoms that substantially affect daily functioning.
Frequency: Varies
Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Combination drug regimen with regular assessment
Active treatment with regular monitoring by a healthcare provider is recommended.
Intravenous Immunoglobulin (IVIG)
IVIG is administered to modulate the immune response and reduce autoimmune attack on peripheral nerves. This is typically given daily for 5 consecutive days in a hospital setting.
Plasma Exchange (Plasmapheresis)
This procedure filters the blood to remove harmful antibodies and inflammatory factors attacking the nerves. Typically requires 4-6 exchange sessions over 2-3 weeks.
Additional treatment options
Intensive Rehabilitation Therapy
A structured physical and occupational therapy program to maintain joint mobility, prevent muscle atrophy, and retrain motor function as nerve recovery progresses.
physical_therapyRespiratory Function Monitoring
Regular monitoring of vital capacity and respiratory muscle strength is essential to detect impending respiratory failure, which is a life-threatening complication requiring urgent intervention.
monitoringNeuropathic Pain Management
Gabapentinoids or other neuropathic pain agents to manage severe pain and paresthesias associated with nerve inflammation.
medicationWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Acute Inflammatory Demyelinating Polyradiculoneuropathy C4551910?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Joint Task Force of the EFNS and PNS. European Federation of Neurological Societies and Peripheral Nerve Society Guideline on management of Guillain-Barré syndrome. J Peripher Nerv Syst. 2020.
Willison HJ, Jacobs BC, van Doorn PA. Guillain-Barré syndrome. Lancet. 2016.
Chevret S, Hughes RA, Annane D. Plasma exchange for Guillain-Barré syndrome. Cochrane Database Syst Rev. 2017.
Rinaldi S,更新的. Autoimmune neuropathies: new insights into pathophysiology and therapeutic strategies. Neurology. 2018.
Medication Comparisons
Compare medications used to treat Acute Inflammatory Demyelinating Polyradiculoneuropathy C4551910. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy