Acute Kidney Injury C2609414
Sudden loss of kidney function, common in hospitalized patients. Treatment focuses on the underlying cause and supporting kidney recovery, sometimes requiring dialysis.
Key facts at a glance
- ICD-10
- N28.9
- ICD-11
- GA00.0
- Body system
- renal
- Severity
- severe
- Chronic
- false
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Fluid overload
Changes in urination or swelling
(renal)Significant symptoms that substantially affect daily functioning.
Frequency: Varies
Decreased urine output
(renal)Electrolyte imbalances
(renal)Fatigue
(renal)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
IV Fluid Resuscitation
Aggressive intravenous fluid therapy to maintain renal perfusion and correct hypovolemia. Choice of fluid depends on electrolyte status and underlying cause.
Renal disease management
Active treatment with regular monitoring by a healthcare provider is recommended.
Renal Replacement Therapy (Dialysis)
When AKI is severe with refractory hyperkalemia, acidosis, fluid overload, or uremic symptoms, dialysis provides renal support and electrolyte correction.
Additional treatment options
Electrolyte and Metabolic Management
Pharmacological and dietary management of hyperkalemia, metabolic acidosis, hyperphosphatemia, and other electrolyte derangements characteristic of AKI.
medicationUrine Output and Renal Function Monitoring
Strict input-output monitoring, daily weights, and serial measurements of creatinine, BUN, and electrolytes to track disease progression and treatment response.
monitoringNephrotoxic Exposure Avoidance
Identification and cessation of all potentially nephrotoxic substances including NSAIDs, certain antibiotics, contrast dyes, and herbal supplements.
lifestyleWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Acute Kidney Injury C2609414?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Kidney Disease Improving Global Outcomes (KDIGO). Clinical practice guideline for acute kidney injury. Kidney Int Suppl. 2012.
Makris K, Spanou L. Acute kidney injury: definition, pathophysiology and clinical phenotypes. Clin Biochem Rev. 2016.
Wald R, McArthur E, Adhikari NK, et al. Changing incidence and outcomes following dialysis-requiring acute kidney injury among critically ill patients: a systematic review and meta-analysis. JAMA Intern Med. 2015.
Sutherland SM, Zappitelli M, Alexander SR, et al. Fluid overload and mortality in children on continuous renal replacement therapy: a prospective observational study. Crit Care Med. 2019.
Medication Comparisons
Compare medications used to treat Acute Kidney Injury C2609414. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy