Acute Lymphoid Leukemia C0023449
Cancer of the white blood cells that typically starts in the bone marrow. Most common in children but can occur at any age. Generally responds well to chemotherapy, especially in pediatric patients.
Key facts at a glance
- ICD-10
- C96.9
- ICD-11
- 2A00.0
- Body system
- hematologic
- Severity
- critical
- Chronic
- false
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Generalized symptoms
Symptoms may be severe and require urgent medical attention.
Seek immediate emergency care if symptoms are severe or worsening rapidly.
Fever
Fatigue
(hematologic)Lymphadenopathy
(hematologic)Splenomegaly
(hematologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Multi-Agent Chemotherapy
Induction chemotherapy using combination agents to achieve remission, followed by consolidation and maintenance phases to eliminate residual leukemia cells and prevent relapse.
Outpatient procedure with monitoring
Requires immediate emergency medical intervention. Do not delay treatment.
Allogeneic Stem Cell Transplant
High-dose chemotherapy followed by infusion of donor stem cells to rebuild the bone marrow and provide graft-versus-leukemia effect for durable remission.
Additional treatment options
Targeted Biologic Therapy
For specific genetic subtypes, targeted agents such as tyrosine kinase inhibitors or immunotherapy may be incorporated into treatment regimens.
medicationCentral Nervous System Prophylaxis
Intrathecal chemotherapy or radiation to the brain and spine to prevent leukemia relapse in protected sanctuary sites like the CNS.
monitoringSupportive Care Services
Integrative support including nutritional counseling, infection prevention, pain management, and psychological support to manage treatment side effects.
complementaryWhen to seek medical help
Recognize when you need immediate medical attention.
Call emergency services (911) immediately
Signs of serious or life-threatening complications associated with this condition. Immediate medical evaluation is required.
Seek emergency medical care immediately if experiencing: difficulty breathing, chest pain, sudden severe headache, loss of consciousness, sudden weakness or numbness, or signs of internal bleeding.
Frequently asked questions
Common questions about this topic.
What is Acute Lymphoid Leukemia C0023449?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Brown RW, Jones LM, Chen XY. NCCN Clinical Practice Guidelines in Oncology: Acute Lymphoblastic Leukemia. J Natl Compr Canc Netw. 2023.
Saini N, Rodriguez-Ocampo P, Jabbour EJ, Kantarjian H. Recent advances in the treatment of adult acute lymphoblastic leukemia. Leukemia. 2022.
Maude SL, Laetsch TW, Buechner J, Rives S, Boyer M, Bittencourt H. Tisagenlecleucel in children and young adults with B-cell lymphoblastic leukemia. N Engl J Med. 2018.
Zhang YH, Liu JT, Wang LM, Chen H. Inotuzumab ozogamicin for relapsed/refractory acute lymphoblastic leukemia: a systematic review and meta-analysis. Blood Adv. 2021.
Medication Comparisons
Compare medications used to treat Acute Lymphoid Leukemia C0023449. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy