Acute Monoblastic Leukemia C0457334
A fast-growing leukemia of immature white blood cells called monocytes. Can occur at any age. Treated with intensive chemotherapy and sometimes stem cell transplant.
Key facts at a glance
- ICD-10
- C96.9
- ICD-11
- 2A00.0
- Body system
- hematologic
- Severity
- critical
- Chronic
- false
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Generalized symptoms
Symptoms may be severe and require urgent medical attention.
Seek immediate emergency care if symptoms are severe or worsening rapidly.
Fatigue
(hematologic)Gum hyperplasia
(hematologic)Fever
(hematologic)Leukemia cutis
(hematologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
AML-Type Induction Chemotherapy
Anthracycline and cytarabine-based induction therapy specifically effective for monoblastic morphology, with consideration for ATRA addition if APL variant excluded.
Elective procedure with pre- and post-procedure care
Requires immediate emergency medical intervention. Do not delay treatment.
Autologous Stem Cell Rescue
Harvesting and storage of patient's own stem cells during remission for later reinfusion after high-dose consolidation chemotherapy.
Additional treatment options
Integrative Medicine Support
Evidence-based complementary therapies including acupuncture for chemotherapy-induced nausea, mind-body practices for anxiety, and botanical support for symptom management.
complementaryPsychiatric Symptom Management
Assessment and treatment of anxiety, depression, and adjustment disorders common in acute leukemia patients, including pharmacotherapy and psychotherapy.
psychologicalWhen to seek medical help
Recognize when you need immediate medical attention.
Call emergency services (911) immediately
Signs of serious or life-threatening complications associated with this condition. Immediate medical evaluation is required.
Seek emergency medical care immediately if experiencing: difficulty breathing, chest pain, sudden severe headache, loss of consciousness, sudden weakness or numbness, or signs of internal bleeding.
Frequently asked questions
Common questions about this topic.
What is Acute Monoblastic Leukemia C0457334?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Döhner H, Estey EH, Grimwade D, et al. Diagnosis and management of AML in adults: 2017 ELN recommendations from an international expert panel. Blood. 2017;129(4):424-447.
Arber DA, Orazi A, Hasserjian RP, et al. International consensus classification of myeloid neoplasms and acute leukemia: integrating morphological, clinical, and genomic data. Blood. 2022;140(10):1200-1228.
Kantarjian HM, Thomas XG, Dmoszynska A, et al. Multicenter, randomized, open-label, phase 3 trial of low-dose cytarabine and all-trans retinoic acid in elderly patients with acute myeloid leukemia. J Clin Oncol. 2012;30(23):2946-2952.
Hoffbrand AV, Steensma DP. Hoffbrand's Essential Haematology. 8th ed. Wiley-Blackwell; 2019. Chapter 20, Acute myeloid leukemia; p. 235-262.
Medication Comparisons
Compare medications used to treat Acute Monoblastic Leukemia C0457334. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy