Acute Myeloblastic Leukemia Without Maturation C0026998
An aggressive leukemia where cancer cells fail to mature properly. Typically affects adults. Intensive chemotherapy needed, often followed by transplant.
Key facts at a glance
- ICD-10
- C96.9
- ICD-11
- 2A00.0
- Body system
- hematologic
- Severity
- critical
- Chronic
- false
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Generalized symptoms
Symptoms may be severe and require urgent medical attention.
Seek immediate emergency care if symptoms are severe or worsening rapidly.
Sudden weakness
Fatigue
(hematologic)Easy bruising
(hematologic)Frequent infections
(hematologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Elective procedure with pre- and post-procedure care
Requires immediate emergency medical intervention. Do not delay treatment.
Intensive Induction Chemotherapy
Aggressive multi-drug chemotherapy regimen designed to rapidly reduce leukemic burden, requiring close inpatient monitoring and supportive care infrastructure.
Allogeneic Stem Cell Transplantation
Curative-intent treatment using donor-derived stem cells after myeloablative chemotherapy, offering graft-versus-leukemia effect particularly beneficial in high-risk disease.
Additional treatment options
Autologous Stem Cell Transplant
Collection and reinfusion of patient's own stem cells after high-dose chemotherapy, offering consolidation without graft-versus-host disease risks.
procedureIntensive Supportive Care
Comprehensive blood product support, antimicrobial prophylaxis, nutritional intervention, and management of tumor lysis syndrome and other complications.
monitoringHypomethylating Agent Therapy
Azacitidine or decitabine for patients ineligible for intensive chemotherapy, offering disease control through epigenetic modification of leukemic cells.
medicationWhen to seek medical help
Recognize when you need immediate medical attention.
Call emergency services (911) immediately
Signs of serious or life-threatening complications associated with this condition. Immediate medical evaluation is required.
Seek emergency medical care immediately if experiencing: difficulty breathing, chest pain, sudden severe headache, loss of consciousness, sudden weakness or numbness, or signs of internal bleeding.
Frequently asked questions
Common questions about this topic.
What is Acute Myeloblastic Leukemia Without Maturation C0026998?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
NCCN. NCCN Clinical Practice Guidelines for Acute Myeloid Leukemia Version 3.2023. Natl Compr Canc Netw Guid. 2023.
Döhner H, Estey EH, Amadori S, et al. Diagnosis and management of acute myeloid leukemia in adults: recommendations from an international expert panel. Blood Adv. 2020.
DiNardo CD, Stein EM, de Botton S, et al. Durable remissions with ivosidenib in IDH1-mutant relapsed or refractory acute myeloid leukemia. Blood. 2019.
Wang ML, Blum KA, Martin P, et al. Long-term follow-up of outcomes in peripheral T-cell lymphoma: a systematic review and meta-analysis. Blood. 2021.
Medication Comparisons
Compare medications used to treat Acute Myeloblastic Leukemia Without Maturation C0026998. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy