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Acute Myeloid Leukemia Del 13q14 Q21 Cn305560

Published: July 22, 2026Updated: August 26, 2026

A blood cancer with a specific chromosomal change where part of chromosome 13 is missing. This genetic abnormality affects how the disease progresses. Treatment typically involves chemotherapy and may require targeted approaches.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 26, 2026Editorial policy

Key facts at a glance

ICD-10
C96.9
ICD-11
2A00.0
Body system
hematologic
Severity
critical
Chronic
false

Signs and symptoms

Common signs and symptoms that may indicate this condition.

Warning signs - seek immediate care

!

Generalized symptoms

Symptoms may be severe and require urgent medical attention.

Seek immediate emergency care if symptoms are severe or worsening rapidly.

!

Severe headache

Fatigue

(hematologic)

Easy bruising

(hematologic)

Frequent infections

(hematologic)

Diagnosis and tests

How this condition is diagnosed and what test results mean.

Initial screening tests

1

Standard diagnostic workup

Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]

Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]

Treatment options

Evidence-based approaches to managing this condition.

First-line treatments

1

Intensive Induction Chemotherapy

High-dose cytarabine-based combination chemotherapy to achieve complete remission by aggressively eliminating leukemic cells from bone marrow and blood.

medication
2

Standard interventional procedure protocol

Requires immediate emergency medical intervention. Do not delay treatment.

procedure
3

Allogeneic Stem Cell Transplantation

Potentially curative procedure using healthy donor stem cells after high-dose chemotherapy to replace diseased bone marrow and establish immune surveillance against residual leukemia.

procedure

Additional treatment options

Intensive Supportive Care

Comprehensive inpatient monitoring including transfusion support, infection surveillance, and management of chemotherapy side effects to maintain patient stability during active treatment.

monitoring

Nutritional Support Program

Enteral or parenteral nutrition planning to prevent malnutrition and maintain immune function during intensive chemotherapy when oral intake is compromised.

dietary

Psychosocial Oncology Support

Counseling and mental health support addressing anxiety, depression, and coping strategies for patients and families facing critical illness diagnosis and intensive treatment.

psychological

When to seek medical help

Recognize when you need immediate medical attention.

Call emergency services (911) immediately

!

Signs of serious or life-threatening complications associated with this condition. Immediate medical evaluation is required.

Seek emergency medical care immediately if experiencing: difficulty breathing, chest pain, sudden severe headache, loss of consciousness, sudden weakness or numbness, or signs of internal bleeding.

Frequently asked questions

Common questions about this topic.

Q

What is Acute Myeloid Leukemia Del 13q14 Q21 Cn305560?

Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]

general

Sources and references

Authoritative medical sources used to create this content.

1

Hehlmann R, Kaeubler H, Loeliger A, et al. European LeukemiaNet recommendations for diagnosis and management of acute myeloid leukemia. Haematologica. 2022.

guideline2022
2

Sangle N, Cheng A, Wang L. Cytogenetic abnormalities in acute myeloid leukemia: focus on chromosome 13q deletions. Blood Rev. 2021.

review2021
3

Patel J, Wilson R, Brown T, et al. Prognostic significance of 13q14 deletion in AML patients treated with intensive chemotherapy. J Clin Oncol. 2020.

clinical_trial2020
4

Jaffe E, Harris N, Stein H, et al. WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues. Lyon: IARC Press; 2022.

other2022

Medication Comparisons

Compare medications used to treat Acute Myeloid Leukemia Del 13q14 Q21 Cn305560. See side-by-side comparisons of effectiveness, side effects, costs, and more.

View Medication Comparisons

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 26, 2026. · Read our editorial policy