Acute Myeloid Leukemia Kit Gene Mutation Cn305577
AML with a KIT gene mutation involves abnormal cell growth. It affects adults and may impact prognosis. Treatment typically includes chemotherapy and targeted therapy.
Key facts at a glance
- ICD-10
- C96.9
- ICD-11
- 2A00.0
- Body system
- hematologic
- Severity
- severe
- Chronic
- false
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Fatigue
(hematologic)Generalized symptoms
(hematologic)Significant symptoms that substantially affect daily functioning.
Frequency: Varies
Fever
(hematologic)Petechiae
(hematologic)Weight loss
(hematologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Anthracycline-Based Induction
Standard 7+3 regimen combining continuous cytarabine with intermittent anthracycline administration. KIT mutation status informs prognosis and may guide intensity decisions.
Medication management with follow-up
Active treatment with regular monitoring by a healthcare provider is recommended.
Diagnostic Bone Marrow Biopsy and Aspirate
Comprehensive morphologic, immunophenotypic, and molecular characterization of disease. KIT mutation identification guides targeted therapy selection and prognostic stratification.
When to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Acute Myeloid Leukemia Kit Gene Mutation Cn305577?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Dohner H, Estey E, Grimwade D, et al. Diagnosis and management of AML in adults: 2017 ELN recommendations from an international expert panel. Blood. 2017.
Cammenga J, Horn S, Bergholz U, et al. Core binding factor acute myeloid leukemia with KIT mutations: prognostic implications. Haematologica. 2015.
Paschka P, Marcucci G, Ruppert AS, et al. Adverse prognostic significance of KIT mutations in adult acute myeloid leukemia with inv(16) and t(8;21). J Clin Oncol. 2006.
Krause DS, Van Etten RA. Tyrosine kinases as targets for cancer therapy. N Engl J Med. 2005.
Medication Comparisons
Compare medications used to treat Acute Myeloid Leukemia Kit Gene Mutation Cn305577. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy