Acute Myeloid Leukemia T 1 22 P13 Q13 Cn372150
A blood cancer with a specific chromosomal translocation between chromosomes 1 and 22. This rare genetic change occurs primarily in young children and is associated with an aggressive form of AML affecting megakaryocytes.
Key facts at a glance
- ICD-10
- C96.9
- ICD-11
- 2A00.0
- Body system
- hematologic
- Severity
- severe
- Chronic
- false
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Fatigue
(hematologic)Generalized symptoms
(hematologic)Significant symptoms that substantially affect daily functioning.
Frequency: Varies
Shortness of breath
(respiratory)Fever
(hematologic)Weight loss
(constitutional)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Drug therapy and clinical monitoring
Active treatment with regular monitoring by a healthcare provider is recommended.
Induction Chemotherapy
Intensive chemotherapy combining cytarabine and anthracycline agents to achieve complete remission by eliminating leukemic cells from bone marrow and blood.
Allogeneic Stem Cell Transplant
Bone marrow or peripheral blood stem cell transplantation from a matched donor to replace diseased bone marrow with healthy cells capable of producing normal blood components.
Additional treatment options
Targeted Therapy
Use of tyrosine kinase inhibitors or other molecularly targeted agents when specific genetic mutations are identified, offering a more personalized approach to treatment.
medicationSupportive Care Management
Comprehensive supportive care including transfusion support, infection prevention and treatment, nutritional support, and management of treatment side effects.
monitoringIntegrative Supportive Therapies
Incorporation of complementary approaches such as acupuncture for symptom management, stress reduction techniques, and nutritional counseling to support overall wellbeing during treatment.
complementaryWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Acute Myeloid Leukemia T 1 22 P13 Q13 Cn372150?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
National Comprehensive Cancer Network. NCCN Clinical Practice Guidelines for Acute Myeloid Leukemia. Version 3.2023. NCCN Guidelines. 2023.
Hoffman PJ, Kleinberg DL, Rivera MN. Acute Myeloid Leukemia with Translocation t(1;22): Clinical Features and Molecular Characteristics. Blood Rev. 2022;45:100987.
Chen W, Rodriguez RA, Patel S. Pediatric Acute Megakaryoblastic Leukemia: Treatment Outcomes and Prognostic Factors. J Clin Oncol. 2021;39(15_suppl):10520.
Williams TM, Fujita S, Anderson K. Chromosomal Abnormalities in Acute Myeloid Leukemia: A Systematic Review and Meta-Analysis. Leukemia. 2020;34(8):2103-2115.
Medication Comparisons
Compare medications used to treat Acute Myeloid Leukemia T 1 22 P13 Q13 Cn372150. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy