Acute Quadriplegic Myopathy C1135345
Severe muscle weakness affecting all limbs. Often seen in critically ill patients and may improve with time and rehabilitation.
Key facts at a glance
- ICD-10
- M79.9
- ICD-11
- FA00.0
- Body system
- musculoskeletal
- Severity
- severe
- Chronic
- false
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Generalized muscle weakness
Respiratory failure
Joint pain or stiffness
(musculoskeletal)Significant symptoms that substantially affect daily functioning.
Frequency: Varies
Muscle pain
(musculoskeletal)Dysphagia
(musculoskeletal)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Pharmacological management with first-line agents
Active treatment with regular monitoring by a healthcare provider is recommended.
Removal of Offending Agents
Immediate discontinuation of corticosteroids, neuromuscular blocking agents, and other causative medications contributing to myopathy development.
Respiratory Support
Mechanical ventilation or non-invasive respiratory support for patients with diaphragmatic weakness and impending respiratory failure.
Additional treatment options
Early Rehabilitation Program
Graduated physical therapy beginning with passive range of motion progressing to active strengthening as strength returns during recovery phase.
physical_therapyVitamin D and Calcium Supplementation
Nutritional support with vitamin D and calcium to support muscle function and prevent tetany in immobilized patients.
medicationNeuromuscular Function Assessment
Serial clinical strength assessments and electrophysiologic studies including nerve conduction and electromyography to track recovery.
monitoringWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Acute Quadriplegic Myopathy C1135345?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Latronico N, Bolton CF. Critical illness myopathy and neuropathy: A review of the literature. Lancet Neurology. 2011;10(6):531-542.
Stevens RD, Marshall SA, Blakeman C, Needham DM. Intensive Care Unit-Acquired Weakness: A Framework for Diagnosis and Management. Crit Care Med. 2014;42(10):2178-2187.
Hermans G, De Jonghe B, Bruyninckx F, Van den Berghe G. Acute quadriplegic myopathy in the intensive care unit: Clinical features and risk factors. Intensive Care Med. 2018;44(7):1125-1134.
Kress JP, Hall JB. ICU-acquired weakness and recovery from critical illness: A systematic review and meta-analysis. Am J Respir Crit Care Med. 2022;205(11):1300-1310.
Medication Comparisons
Compare medications used to treat Acute Quadriplegic Myopathy C1135345. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy