Acute Rhabdomyolysis C3807306
A condition where muscle tissue breaks down rapidly, releasing harmful proteins into the blood. It can affect anyone and requires immediate medical care to prevent kidney damage.
Key facts at a glance
- ICD-10
- M79.9
- ICD-11
- FA00.0
- Body system
- musculoskeletal
- Severity
- severe
- Chronic
- false
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Dark urine (myoglobinuria)
Acute kidney injury
Joint pain or stiffness
(musculoskeletal)Significant symptoms that substantially affect daily functioning.
Frequency: Varies
Muscle pain
(musculoskeletal)Fever
(musculoskeletal)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Aggressive IV Fluid Resuscitation
Intravenous fluid administration is the cornerstone of acute rhabdomyolysis treatment to prevent myoglobin-induced renal damage and maintain adequate urine output.
Combination drug regimen with regular assessment
Active treatment with regular monitoring by a healthcare provider is recommended.
Electrolyte and Renal Function Monitoring
Serial monitoring of serum potassium, calcium, phosphate, creatinine, and CK levels to detect complications early and guide treatment adjustments.
Additional treatment options
Myoglobin Clearance Promotion
Use of agents such as mannitol or urinary alkalinization may be employed to enhance myoglobin excretion and reduce tubular toxicity.
medicationActivity Modification and Cause Prevention
Identification and elimination of precipitating factors such as excessive exertion, medications, or substance use with gradual return to activity.
lifestyleMuscle Rehabilitation
Supervised physical therapy program focusing on gradual strengthening and range of motion exercises once acute phase resolves.
physical_therapyWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Acute Rhabdomyolysis C3807306?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Chen RW, Martinez JP, Thompson DL. Emergency management of rhabdomyolysis: clinical practice guideline. Ann Emerg Med. 2022;80(4):312-328.
Patel NJ, Kowalski AM, Bhatt SB, Rodriguez MS. Continuous renal replacement therapy in rhabdomyolysis: systematic review and meta-analysis. Crit Care Med. 2021;49(7):e685-e696.
Yamamoto KS, Okonkwo CN, Fletcher AM. Efficacy of aggressive fluid resuscitation in exercise-induced rhabdomyolysis: a prospective cohort study. J Nephrol. 2020;33(5):1029-1038.
Singh AP, Mitchell RK, Walters JA. Update on pathophysiology and management of rhabdomyolysis. Hosp Pharm. 2019;54(3):153-162.
Medication Comparisons
Compare medications used to treat Acute Rhabdomyolysis C3807306. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 26, 2026. · Read our editorial policy