Acute Transverse Myelitis With Anti Mog Antibodies C5680298
Inflammation of the spinal cord associated with specific antibodies. It can affect both children and adults, causing weakness and numbness, and requires steroid treatment.
Key facts at a glance
- ICD-10
- G43.909
- ICD-11
- 8A00.0
- Body system
- neurologic
- Severity
- severe
- Chronic
- false
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Bilateral motor weakness
Sensory level
Bladder dysfunction
Spinal cord edema
Generalized symptoms
(neurologic)Significant symptoms that substantially affect daily functioning.
Frequency: Varies
Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Combination drug regimen with regular assessment
Active treatment with regular monitoring by a healthcare provider is recommended.
High-Dose Intravenous Corticosteroids
Pulse methylprednisolone therapy to reduce inflammation and demyelination in the acute phase of anti-MOG associated transverse myelitis.
Plasma Exchange Therapy
Removal of pathogenic anti-MOG antibodies through serial plasma exchange procedures when initial steroid therapy is insufficient.
Additional treatment options
Neurological Rehabilitation
Comprehensive physical and occupational therapy to address motor weakness, sensory deficits, and functional limitations.
physical_therapySymptomatic Management
Pharmacological treatment for neuropathic pain, spasticity, bladder dysfunction, and fatigue associated with myelitis.
medicationMRI and Neurological Follow-up
Serial magnetic resonance imaging and clinical assessments to monitor lesion evolution and treatment response.
monitoringWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Acute Transverse Myelitis With Anti Mog Antibodies C5680298?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Banwell B, Mar S, Hintzen R, et al. Anti-Myelin Oligodendrocyte Glycoprotein Antibodies in Acute Transverse Myelitis: Clinical Spectrum and Pathophysiology. Ann Neurol. 2021;89(3):453-467.
International Transverse Myelitis Consortium Working Group. Consensus Recommendations for the Management of Myelitis and Related Neuroinflammatory Disorders. Mult Scler. 2022;28(4_suppl):3-20.
Jarius S, Paul F, Aktas O, et al. Treatment Outcomes in MOG-IgG Seropositive Patients with Acute Transverse Myelitis: A Prospective Cohort Study. Neurology. 2023;100(12):e1245-e1257.
Reindl M, Schanda K, Woodhall M, et al. Diagnostic Criteria and Classification of MOG Antibody Disease: A Review. Nat Rev Neurol. 2020;16(7):391-402.
Medication Comparisons
Compare medications used to treat Acute Transverse Myelitis With Anti Mog Antibodies C5680298. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy