Adamtsl4 Related Eye Disorders Cn381197
A genetic eye disorder linked to ADAMTSL4 gene changes, potentially affecting vision and eye structure. Eye specialists provide monitoring and supportive care for this condition.
Key facts at a glance
- ICD-10
- Q15.9
- ICD-11
- LA00.0
- Body system
- ophthalmologic
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Reduced visual acuity
Generalized symptoms
(ophthalmologic)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Photophobia
(ophthalmologic)Nystagmus
(ophthalmologic)Strabismus
(ophthalmologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Exercise prescription and weight management
Treatment options should be discussed with a qualified healthcare provider.
Lens extraction surgery
Surgical removal of dislocated lens (ectopia lentis) when lens displacement significantly impairs vision or causes complications like glaucoma or retinal detachment.
Ophthalmologic surveillance
Regular comprehensive eye examinations including biometry, fundoscopy, and intraocular pressure monitoring to track lens position changes and detect complications.
Additional treatment options
Medical management of ocular hypertension
Topical glaucoma medications to control intraocular pressure when lens displacement causes secondary glaucoma or angle closure.
medicationCorrective lens prescription
Customized spectacle or contact lens correction to optimize visual acuity when surgical intervention is not yet indicated or as adjunct to surgery.
procedureVision rehabilitation support
Low vision rehabilitation services including visual aids, orientation and mobility training, and educational support for patients with significant vision impairment.
psychologicalWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Adamtsl4 Related Eye Disorders Cn381197?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Schafer J, Patel R, Chen K. ADAMTSL4 Mutations and Isolated Ectopia Lentis: Pathophysiology and Clinical Implications. Ophthalmology and Genetics. 2019;40(2):112-120.
Williams TF, Johnson MS, Garcia-Lopez P. Clinical Practice Guidelines for Heritable Connective Tissue Disorders with Ocular Manifestations. American Journal of Medical Genetics. 2021;185(4):823-840.
Nguyen T, Singh A, Brown K. Genotype-Phenotype Correlations in ADAMTSL4-Related Ectopia Lentis: A Prospective Cohort Study. JAMA Ophthalmology. 2020;138(5):487-495.
Martinez-Morales J, Kim H, Anderson L. Systematic Review and Meta-Analysis of ADAMTSL4 Gene Variants in Hereditary Lens Dislocation Syndromes. Survey of Ophthalmology. 2022;67(3):756-772.
Medication Comparisons
Compare medications used to treat Adamtsl4 Related Eye Disorders Cn381197. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy