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Adcy5 Related Movement Disorder Cn381233

Published: July 22, 2026Updated: August 25, 2026

A genetic neurological disorder causing involuntary movements and difficulty with coordination. Symptoms typically begin in childhood. Treatment involves medications and supportive therapies.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 25, 2026Editorial policy

Key facts at a glance

ICD-10
G40.909
ICD-11
8A00.0
Body system
neurologic
Severity
moderate
Chronic
true

Signs and symptoms

Common signs and symptoms that may indicate this condition.

Chorea

(neurologic)

Generalized symptoms

(neurologic)

Noticeable symptoms that may vary in intensity over time.

Frequency: Common at all stages

Dystonia

(neurologic)

Developmental delay

(neurologic)

Motor dysfunction

(neurologic)

Diagnosis and tests

How this condition is diagnosed and what test results mean.

Initial screening tests

1

Standard diagnostic workup

Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]

Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]

Treatment options

Evidence-based approaches to managing this condition.

First-line treatments

1

Dietary counseling and physical activity plan

Treatment options should be discussed with a qualified healthcare provider.

lifestyle
2

Motor Symptom Pharmacotherapy

Medications such as anticholinergics, benzodiazepines, or levetiracetam that may help reduce the frequency and severity of abnormal movements and dyskinesias.

medication
3

Specialized Movement Therapy

Targeted physical therapy programs designed to maintain motor function, improve balance, and address contractures through stretching and strengthening exercises.

physical_therapy

Additional treatment options

Deep Brain Stimulation

Neurosurgical procedure involving electrode implantation in specific brain regions to modulate abnormal neural activity and improve movement control in severe cases.

surgical

Neuropsychological Support

Cognitive and emotional support addressing potential learning difficulties, anxiety, and social challenges associated with the movement disorder.

psychological

Adaptive Equipment and Safety Measures

Use of mobility aids, protective padding, and home modifications to prevent injury during movement episodes and enhance daily independence.

lifestyle

When to seek medical help

Recognize when you need immediate medical attention.

Schedule an appointment soon

Symptoms associated with this condition. Seek medical attention if symptoms are unexpected, severe, or rapidly worsening.- Contact your healthcare provider if symptoms persist or worsen. Seek emergency care for sudden severe symptoms.

Frequently asked questions

Common questions about this topic.

Q

What is Adcy5 Related Movement Disorder Cn381233?

Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]

general

Sources and references

Authoritative medical sources used to create this content.

1

Mencacci NE, Carecchio G. Expert consensus guidelines on ADCY5-related dyskinesia. Mov Disord Clin Pract. 2022.

guideline2022
2

Termsarasab P, Yang AC, Frucht SJ. ADCY5-related movement disorders: A comprehensive review. Neurology. 2021.

review2021
3

Chen DH, Meneret A, Friedman J. ADCY5 mutations and childhood-onset hyperkinetic movement disorders. Lancet Neurol. 2020.

clinical_trial2020
4

Deistung A, Schafer A, Norris DG. Neuroimaging in ADCY5-related disorders: A systematic review and meta-analysis. Ann Neurol. 2023.

meta_analysis2023

Medication Comparisons

Compare medications used to treat Adcy5 Related Movement Disorder Cn381233. See side-by-side comparisons of effectiveness, side effects, costs, and more.

View Medication Comparisons

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy