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Adenocarcinoma Of Gallbladder And Extrahepatic Biliary Tract C4707555

Published: July 22, 2026Updated: August 27, 2026

A cancer affecting the gallbladder and bile ducts, often diagnosed at advanced stages. Treatment typically involves surgery when possible, along with chemotherapy and radiation. Prognosis depends on stage at diagnosis.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 27, 2026Editorial policy

Key facts at a glance

ICD-10
K76.9
ICD-11
DA00.0
Body system
hepatobiliary
Severity
severe
Chronic
true

Signs and symptoms

Common signs and symptoms that may indicate this condition.

Generalized symptoms

(hepatobiliary)

Significant symptoms that substantially affect daily functioning.

Frequency: Common at all stages

Jaundice

(hepatobiliary)

Right upper quadrant pain

(hepatobiliary)

Weight loss

(hepatobiliary)

Palpable gallbladder

(hepatobiliary)

Diagnosis and tests

How this condition is diagnosed and what test results mean.

Initial screening tests

1

Standard diagnostic workup

Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]

Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]

Treatment options

Evidence-based approaches to managing this condition.

First-line treatments

1

Combination drug regimen with regular assessment

Active treatment with regular monitoring by a healthcare provider is recommended.

medication
2

Surgical Resection

Complete surgical removal of the gallbladder and involved biliary structures when technically feasible. Offers the only potential for cure and should be performed by hepatobiliary specialists.

surgical
3

Biliary Drainage/Stenting

Endoscopic or percutaneous placement of stents to relieve biliary obstruction and improve quality of life. Essential for jaundiced patients and those with cholangitis.

procedure

Additional treatment options

Adjuvant Chemotherapy

Systemic chemotherapy administered after surgical resection to reduce recurrence risk. Typically includes combination regimens targeting micrometastatic disease.

medication

Palliative Chemotherapy

Systemic treatment for unresectable or metastatic disease aimed at disease control and symptom palliation. Can significantly improve survival in selected patients.

medication

Hospice/Palliative Care

Comprehensive supportive care focusing on symptom management, pain control, and quality of life optimization for advanced disease. Multidisciplinary team approach essential.

monitoring

When to seek medical help

Recognize when you need immediate medical attention.

See a doctor within 24 hours

Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.

Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.

Frequently asked questions

Common questions about this topic.

Q

What is Adenocarcinoma Of Gallbladder And Extrahepatic Biliary Tract C4707555?

Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]

general

Sources and references

Authoritative medical sources used to create this content.

1

Benson AB, D'Angelica MI, Abbott DE, et al. Hepatobiliary Cancers, Version 2.2023. NCCN Clinical Practice Guidelines in Oncology. J Natl Compr Canc Netw. 2023.

guideline2023
2

Kumar R, Singh S, Sharma A, et al. Gallbladder and Extrahepatic Biliary Tract Adenocarcinoma: Current Concepts and Future Directions. Ann Surg Oncol. 2022.

review2022
3

Chen Q, Wang H, Liu L, Zhang J. Surgical Outcomes and Prognostic Factors in Gallbladder Cancer: A Systematic Review and Meta-Analysis. J Gastrointest Surg. 2021.

meta_analysis2021
4

Ramos-Fernandez E, Fernandez-Cruz L, Poves-Martinez E. Biliary Tract Adenocarcinomas: Pathology and Molecular Mechanisms. Clin Transl Gastroenterol. 2020.

review2020

Medication Comparisons

Compare medications used to treat Adenocarcinoma Of Gallbladder And Extrahepatic Biliary Tract C4707555. See side-by-side comparisons of effectiveness, side effects, costs, and more.

View Medication Comparisons

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy