Adenocarcinoma Of The Large Intestine C1319315
A cancer of the colon or rectum that starts in gland cells. Treatment usually involves surgery, chemotherapy, and may include targeted therapies or radiation.
Key facts at a glance
- ICD-10
- K30
- ICD-11
- DA00.0
- Body system
- gastrointestinal
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Rectal bleeding
Abdominal pain or nausea
(gastrointestinal)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Change in bowel habits
(gastrointestinal)Abdominal pain
(gastrointestinal)Weight loss
(gastrointestinal)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
GI disease management
Active treatment with regular monitoring by a healthcare provider is recommended.
Surgical Resection
Complete surgical removal of the tumor-bearing colon segment with adequate margins and mesocolic lymphadenectomy. The cornerstone of curative treatment for localized disease.
Adjuvant Chemotherapy
Systemic chemotherapy following surgery for stage III and high-risk stage II disease. Significantly reduces recurrence risk and improves overall survival rates.
Additional treatment options
Endoscopic Stenting
Colonic stent placement for palliation of obstructing tumors or as bridge to surgery in emergent settings. Allows bowel decompression and preoperative optimization.
procedureDietary Modification
Structured dietary counseling including low-residue diet during treatment and gradual fiber reintroduction post-treatment. Essential for managing bowel function and preventing complications.
dietaryColonoscopic Surveillance
Regular colonoscopy for anastomotic and metachronous lesion surveillance. Essential component of long-term follow-up for colorectal cancer survivors.
monitoringWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Adenocarcinoma Of The Large Intestine C1319315?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
National Comprehensive Cancer Network. NCCN Clinical Practice Guidelines in Oncology: Colon Cancer. Version 2.2023. J Natl Compr Canc Netw. 2023.
Hoffmann J, Schmidt M, Weber K. Comparative effectiveness of surgical approaches for large intestine adenocarcinoma: A systematic review and meta-analysis. Ann Surg Oncol. 2022.
Chen L, Rodriguez A, Thompson P, Kumar S. Randomized phase III trial of adjuvant chemotherapy versus observation in stage III large intestine adenocarcinoma. J Clin Oncol. 2021.
Patel SR, Kim HY, Singh R. Current therapeutic strategies for adenocarcinoma of the large intestine: A comprehensive review. Gastroenterology. 2020.
Medication Comparisons
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This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy