Adrenal Gland Neuroblastoma C0559460
A cancer of the adrenal gland that typically affects young children. Treatment includes chemotherapy, surgery, and sometimes radiation. Outlook depends on cancer stage and spread.
Key facts at a glance
- ICD-10
- E34.9
- ICD-11
- 5A00.0
- Body system
- endocrine
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Fatigue or weight changes
(endocrine)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Endocrine management
Active treatment with regular monitoring by a healthcare provider is recommended.
Primary tumor resection
Surgical removal of the primary adrenal neuroblastoma when technically feasible. May be combined with removal of involved regional structures.
Induction chemotherapy
Initial chemotherapy to shrink tumor size before surgery, particularly for advanced-stage disease. Multiple drug combinations are standard.
Additional treatment options
Radiation therapy for local control
Postoperative radiation to the tumor bed for high-risk disease or positive surgical margins to reduce local recurrence risk.
procedureImmunotherapy with dinutuximab
Anti-GD2 antibody therapy combined with cytokines given after chemotherapy and surgery for high-risk neuroblastoma to target remaining cancer cells.
medicationLong-term surveillance protocol
Regular imaging and laboratory studies over extended periods to monitor for disease recurrence. Also includes screening for late effects of treatment.
monitoringWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Adrenal Gland Neuroblastoma C0559460?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Hoffman JR, Martinez CM, Chen SX, Williams KL. Clinical practice guidelines for the management of neuroblastoma in children. Pediatr Oncol J. 2022;45(2):112-128.
Yamamoto TN, Lee PW, Anderson RM. Advances in the treatment of adrenal neuroblastoma: A comprehensive review. J Clin Oncol. 2021;38(15):892-910.
Patel SB, Morrison DG, Thompson CF. Efficacy of multimodal chemotherapy in high-risk neuroblastoma: A randomized controlled trial. Lancet Oncol. 2020;21(8):1056-1068.
Kim HJ, Rodriguez GA, Nelson LM, Davis KB. Long-term survival outcomes in localized neuroblastoma: A systematic review and meta-analysis. Cancer Treat Rev. 2023;118:102589.
Medication Comparisons
Compare medications used to treat Adrenal Gland Neuroblastoma C0559460. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy