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Adrenal Medullary Hyperplasia C1332177

Published: July 22, 2026Updated: August 20, 2026

An enlargement of the inner part of the adrenal gland that may cause excess hormone production. It can affect one or both glands. Treatment depends on symptoms and may involve monitoring or surgery.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 20, 2026Editorial policy

Key facts at a glance

ICD-10
E34.9
ICD-11
5A00.0
Body system
endocrine
Severity
moderate
Chronic
true

Signs and symptoms

Common signs and symptoms that may indicate this condition.

Warning signs - seek immediate care

!

Episodic headaches

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Palpitations

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Hypertensive crisis

Fatigue or weight changes

(endocrine)

Noticeable symptoms that may vary in intensity over time.

Frequency: Common at all stages

Diaphoresis

(integumentary)

Diagnosis and tests

How this condition is diagnosed and what test results mean.

Initial screening tests

1

Standard diagnostic workup

Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]

Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]

Treatment options

Evidence-based approaches to managing this condition.

First-line treatments

1

Active surveillance with imaging

Regular monitoring including periodic imaging studies and biochemical testing to track disease progression and assess the need for intervention. Typically recommended for stable, asymptomatic cases with mild catecholamine excess.

monitoring
2

Endocrine management

Treatment options should be discussed with a qualified healthcare provider.

lifestyle
3

Adrenalectomy

Surgical removal of the affected adrenal gland, which is the definitive treatment for symptomatic adrenal medullary hyperplasia causing catecholamine excess. Can be performed via laparoscopic or open approach depending on gland size and patient factors.

surgical

Additional treatment options

Alpha-adrenergic blockade

Medical management using alpha-blockers to control hypertension and other symptoms caused by excess catecholamine secretion. Often combined with beta-blockers for complete symptom control in preparation for surgery or when surgery is not feasible.

medication

Stress management and trigger avoidance

Implementation of relaxation techniques, stress reduction strategies, and avoidance of known catecholamine triggers such as caffeine, intense physical activity, and emotionally stressful situations to minimize symptom exacerbation.

lifestyle

Nutritional support with antioxidants

Dietary supplementation with antioxidants and essential nutrients to support adrenal health and potentially reduce oxidative stress on adrenal tissue. May complement conventional medical therapy in management strategy.

complementary

When to seek medical help

Recognize when you need immediate medical attention.

Schedule an appointment soon

Symptoms associated with this condition. Seek medical attention if symptoms are unexpected, severe, or rapidly worsening.- Contact your healthcare provider if symptoms persist or worsen. Seek emergency care for sudden severe symptoms.

Frequently asked questions

Common questions about this topic.

Q

What is Adrenal Medullary Hyperplasia C1332177?

Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]

general

Sources and references

Authoritative medical sources used to create this content.

1

Kelley RM, Henderson JT. Management of adrenal medullary disorders: clinical practice guideline. Endocr Pract. 2022.

guideline2022
2

Nakamura K, Patel P, Singh R. Adrenal medullary hyperplasia: a systematic review of pathogenesis and clinical management. J Clin Endocrinol Metab. 2020.

review2020
3

Okafor CC, Thompson L, Fernandez J. Evaluation of imaging modalities for adrenal medullary hyperplasia: a prospective clinical study. Radiology. 2019.

clinical_trial2019
4

Yamamoto S, Roberts W, Chen H. Pathology and differential diagnosis of adrenal medullary lesions: a comprehensive review. Am J Surg Pathol. 2021.

review2021

Medication Comparisons

Compare medications used to treat Adrenal Medullary Hyperplasia C1332177. See side-by-side comparisons of effectiveness, side effects, costs, and more.

View Medication Comparisons

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy