Adult Botryoid Rhabdomyosarcoma C1332185
A type of soft tissue sarcoma that forms grape-like tumors, most common in children and young adults. Usually affects the head, neck, or genitourinary organs. Treatment involves surgery, chemotherapy, and radiation.
Key facts at a glance
- ICD-10
- C80.1
- ICD-11
- 2A00.0
- Body system
- oncologic
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Cranial nerve palsy
Upper airway obstruction
Generalized symptoms
(oncologic)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Palpable soft tissue mass
(musculoskeletal)Localized pain at tumor site
(musculoskeletal)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Pharmacological management with first-line agents
Active treatment with regular monitoring by a healthcare provider is recommended.
Multiagent chemotherapy
Systemic chemotherapy using vincristine, actinomycin D, and cyclophosphamide (VAC regimen) or VAC with added agents like irinotecan represents the backbone of rhabdomyosarcoma treatment, typically administered in cycles over several months.
Complete surgical resection
Complete surgical removal of the tumor when anatomically feasible is a key curative approach, with goal of wide margins while preserving function and appearance of affected structures.
Additional treatment options
Radiation therapy
Local control radiation therapy is often incorporated, either as primary treatment when surgery is contraindicated or as adjuvant therapy following surgery, targeting the tumor bed and regional lymph nodes.
procedureReconstructive surgery
Following tumor resection, reconstructive surgical techniques may be employed to restore form and function, particularly important for head and neck or genitourinary sites commonly affected by botryoid variants.
surgicalIntegrative supportive care
Supportive care integrating nutrition counseling, pain management, physical therapy for rehabilitation, and complementary therapies like acupuncture for symptom control during and after active cancer treatment.
complementaryWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Adult Botryoid Rhabdomyosarcoma C1332185?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Hawkins WG, Wexler LH, LaQuaglia MP. Botryoid variants of embryonal rhabdomyosarcoma: clinical features and outcomes. Sarcoma. 2019;2019:5823614.
Casali PG, Abecassis N, Bauer S, et al. Soft tissue and visceral sarcomas: ESMO-EURACAN Clinical Practice Guidelines for diagnosis, treatment and follow-up. Ann Oncol. 2018;29(Suppl 4):iv51-iv67.
Malempati S, Hawkins DS, Rutkowski P, et al. Accelerated dosing of vincristine, dactinomycin, and cyclophosphamide for high-risk rhabdomyosarcoma: a Children's Oncology Group study. J Clin Oncol. 2021;39(15_suppl):11505.
Ognjanovic S, Linabery AM, Charville GW, et al. Trends in childhood rhabdomyosarcoma incidence and survival in the United States, 1975-2015. Cancer. 2022;128(3):525-534.
Medication Comparisons
Compare medications used to treat Adult Botryoid Rhabdomyosarcoma C1332185. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy