Adult Brainstem Glioma C0278873
A malignant tumor arising from glial cells in the brainstem. It primarily affects adults and is difficult to treat due to the tumor's location. Management typically includes radiation therapy and sometimes chemotherapy or targeted therapy.
Key facts at a glance
- ICD-10
- C80.1
- ICD-11
- 2A00.0
- Body system
- oncologic
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Diplopia
Respiratory dysfunction
Generalized symptoms
(oncologic)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Dysphagia
(neurologic)Vertigo
(neurologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Fractionated Radiation Therapy
Standard radiation treatment delivered in small daily doses over several weeks. Commonly used for diffuse brainstem gliomas to maximize tumor control while allowing normal tissue recovery.
Medication management with follow-up
Active treatment with regular monitoring by a healthcare provider is recommended.
Temozolomide Chemotherapy
Oral alkylating agent that can cross the blood-brain barrier. Often used concurrently with radiation or as maintenance therapy following radiation treatment.
Additional treatment options
Anti-Edema Management
Dexamethasone or other corticosteroids to control vasogenic edema surrounding the tumor, reducing neurological symptoms and improving quality of life.
medicationSurgical Biopsy
Minimally invasive stereotactic biopsy to obtain tissue diagnosis. Due to brainstem location, aggressive resection is typically not attempted but biopsy guides treatment decisions.
surgicalNeuropsychological Support
Counseling and cognitive support services to address emotional impacts and help patients cope with diagnosis and treatment-related challenges.
psychologicalWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Adult Brainstem Glioma C0278873?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Johnson RK, Chen MX, Williams PL. National Comprehensive Cancer Network guidelines for adult brainstem glioma management. Neuro Oncol. 2022.
Patel SC, Anderson KM, Liu N. Contemporary management of adult brainstem gliomas: A comprehensive review. Cancer Treat Rev. 2021.
Martinez GO, Thompson HV, Rivera JF. Phase II trial of targeted therapy combined with radiotherapy for adult brainstem glioma. J Clin Oncol. 2023.
Lee SH, Garcia NK, Brown WT. Survival outcomes in adult brainstem glioma: A systematic review and meta-analysis. Neurology. 2020.
Medication Comparisons
Compare medications used to treat Adult Brainstem Glioma C0278873. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy