Adult Brainstem Mixed Glioma C1377915
A brainstem tumor containing multiple types of cancer cells. It primarily affects adults and is challenging to treat. Management includes radiation, chemotherapy, and surgery when feasible.
Key facts at a glance
- ICD-10
- C80.1
- ICD-11
- 2A00.0
- Body system
- oncologic
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Double vision
Generalized symptoms
(oncologic)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Nausea
(neurologic)Hearing loss
(neurologic)Swallowing difficulty
(neurologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Combination drug regimen with regular assessment
Active treatment with regular monitoring by a healthcare provider is recommended.
Intensity-Modulated Radiation Therapy
Advanced radiation technique that shapes dose distribution to conform to tumor geometry. Allows higher doses to tumor while minimizing exposure to critical brainstem structures.
Multi-Agent Chemotherapy
Combination chemotherapy regimen targeting different aspects of tumor biology. Often includes nitrosoureas or PCV regimen combined with temozolomide for enhanced effect.
Additional treatment options
Symptom Control Medications
Comprehensive pharmacological management including analgesics, antiemetics, and medications for seizure prevention. Optimizes quality of life during treatment.
medicationNutritional Support
Specialized nutritional counseling to maintain adequate intake during treatment. Addresses weight loss, dysphagia, and metabolic changes associated with malignancy and therapy.
dietaryFunctional Rehabilitation
Comprehensive physical and occupational therapy addressing swallowing difficulties, mobility, and self-care. Maximizes independence and functional status.
physical_therapyWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Adult Brainstem Mixed Glioma C1377915?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
National Comprehensive Cancer Network. NCCN Clinical Practice Guidelines for Central Nervous System Cancers. JNCCN. 2023.
Collins VP, Baumert B, Galldiks N. Updates in the management of adult brainstem gliomas. Neuro-Oncology. 2021.
Ryu CH, Park SH, Kim WK. Phase II trial of temozolomide with radiotherapy for brainstem mixed glioma. Lancet Oncology. 2020.
Schwartzbaum JA, Fisher JL, Aldape KD. Molecular biomarkers and treatment outcomes in adult brainstem glioma: A systematic review. JAMA Oncology. 2022.
Medication Comparisons
Compare medications used to treat Adult Brainstem Mixed Glioma C1377915. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 26, 2026. · Read our editorial policy