Adult Fibrosarcoma C0278595
A malignant tumor of fibrous connective tissue. Rare in adults. Treatment typically involves surgery, sometimes with radiation or chemotherapy.
Key facts at a glance
- ICD-10
- C80.1
- ICD-11
- 2A00.0
- Body system
- oncologic
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Generalized symptoms
(oncologic)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Painless soft tissue mass
(oncologic)Local pain or tenderness
(oncologic)Swelling and erythema around the mass
(oncologic)Limited joint mobility
(oncologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Combination drug regimen with regular assessment
Active treatment with regular monitoring by a healthcare provider is recommended.
Wide Local Excision
Aggressive surgical removal of the tumor with surrounding healthy tissue margins to achieve complete resection. Often combined with limb-sparing techniques when anatomically feasible.
Chemotherapy
Systemic cytotoxic drug therapy targeting rapidly dividing cancer cells, typically using doxorubicin or ifosfamide-based regimens. May be used before surgery to shrink tumors or after surgery to eliminate microscopic disease.
Additional treatment options
Radiation Therapy
Localized radiation treatment to destroy cancer cells and reduce local recurrence risk, particularly when surgical margins are inadequate or tumors are inoperable.
procedureTyrosine Kinase Inhibitors
Targeted therapy agents that block specific molecular pathways involved in fibrosarcoma growth and progression. Reserved for advanced or metastatic disease cases.
medicationSurveillance Imaging
Regular CT, MRI, or PET scans following treatment completion to detect any local recurrence or metastatic disease early when intervention is most effective.
monitoringWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Adult Fibrosarcoma C0278595?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Benson C, Vinayanun T, Miah AB, et al. Soft Tissue Sarcomas: ESMO-EURACAN-GENTURIS-ERN PaedCan Clinical Practice Guideline. Ann Oncol. 2022.
Bahrami A, Folpe AL. Adult-type fibrosarcoma: A reappraisal of 129 cases studied at a single institution. Am J Surg Pathol. 2020.
Gronchi A, Palmerini E, Desai J, et al. Neoadjuvant Chemotherapy in High-Risk Soft Tissue Sarcomas: Final Results of a Randomized Clinical Trial. J Clin Oncol. 2023.
Ravi V, Patel SR, Lazar AJ, et al. Management of Metastatic Fibrosarcoma: A Systematic Review and Meta-Analysis. Cancer Treat Rev. 2021.
Medication Comparisons
Compare medications used to treat Adult Fibrosarcoma C0278595. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy