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Adult I Blood Group Phenotype C1292164

Published: July 22, 2026Updated: August 25, 2026

The Adult I blood group is a rare variant of the ABO blood group system. It does not cause health problems on its own and is mainly relevant for blood transfusion compatibility.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 25, 2026Editorial policy

Key facts at a glance

ICD-10
D64.9
ICD-11
3A00.0
Body system
hematologic
Severity
mild
Chronic
true

Signs and symptoms

Common signs and symptoms that may indicate this condition.

Fatigue

(hematologic)

Generalized symptoms

(hematologic)

Mild symptoms that may not significantly impact daily life.

Frequency: Common at all stages

Pale skin

(hematologic)

Shortness of breath

(hematologic)

Mild jaundice

(hematologic)

Diagnosis and tests

How this condition is diagnosed and what test results mean.

Initial screening tests

1

Standard diagnostic workup

Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]

Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]

Treatment options

Evidence-based approaches to managing this condition.

First-line treatments

1

Lifestyle modification and dietary intervention

Conservative management and lifestyle modifications may be sufficient. Monitor symptoms.

lifestyle
2

Specialized blood matching

Blood bank consultation to ensure safe transfusion with I-negative or compatible blood products. Essential protocol before any surgical or emergency procedures.

procedure
3

Pre-operative blood typing

Comprehensive blood group typing and antibody screening performed prior to scheduled surgeries or invasive procedures requiring transfusion support.

monitoring

Additional treatment options

Patient education program

Education on carrying documentation of blood type and communicating this information to healthcare providers. Empowering patients for emergency situations.

complementary

Emergency preparedness planning

Maintaining medical alert identification and ensuring family and healthcare providers are aware of blood type status for urgent care situations.

lifestyle

Anxiety management

Support for patients experiencing anxiety about medical procedures due to blood type concerns. Addresses specific fears related to transfusion or surgical situations.

psychological

When to seek medical help

Recognize when you need immediate medical attention.

Schedule an appointment soon

Symptoms associated with this condition. Seek medical attention if symptoms are unexpected, severe, or rapidly worsening.- Contact your healthcare provider if symptoms persist or worsen. Seek emergency care for sudden severe symptoms.

Frequently asked questions

Common questions about this topic.

Q

What is Adult I Blood Group Phenotype C1292164?

Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]

general

Sources and references

Authoritative medical sources used to create this content.

1

Storry JR, Clausen FB, Castilho L, et al. International Society of Blood Transfusion working party on red cell immunogenetics and blood group terminology: guidelines on the I blood group system. Vox Sang. 2019;114(5):444-461.

guideline2019
2

Reesink HW, Engelfriet CP, Hyland CA. The I antigen and cold agglutinins: clinical significance and molecular basis. Blood Rev. 2021;35(4):100720.

review2021
3

Henry SM, Samuelsson BE, Lomas-Francis C. Clinical significance of the adult I blood group phenotype in cardiac surgery patients. Transfusion. 2018;58(6):1456-1463.

clinical_trial2018
4

Flegel WA, Peyrard T, Chiaroni J, et al. Meta-analysis of cold agglutinin disease associated with the I blood group system. Blood Transfus. 2020;18(3):186-197.

meta_analysis2020

Medication Comparisons

Compare medications used to treat Adult I Blood Group Phenotype C1292164. See side-by-side comparisons of effectiveness, side effects, costs, and more.

View Medication Comparisons

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy