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Adult Kidney Wilms Tumor C1332219

Published: July 22, 2026Updated: August 25, 2026

A rare kidney cancer, typically seen in children but occasionally occurring in adults. Treatment usually requires surgery and chemotherapy. Adult cases often require more intensive treatment and carry a more cautious outlook.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 25, 2026Editorial policy

Key facts at a glance

ICD-10
C80.1
ICD-11
2A00.0
Body system
oncologic
Severity
severe
Chronic
true

Signs and symptoms

Common signs and symptoms that may indicate this condition.

Abdominal mass

(genitourinary)

Generalized symptoms

(oncologic)

Significant symptoms that substantially affect daily functioning.

Frequency: Common at all stages

Hematuria

(genitourinary)

Flank pain

(genitourinary)

Weight loss

(general)

Diagnosis and tests

How this condition is diagnosed and what test results mean.

Initial screening tests

1

Standard diagnostic workup

Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]

Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]

Treatment options

Evidence-based approaches to managing this condition.

First-line treatments

1

Nephrectomy

Surgical removal of the affected kidney, which may be partial for small tumors or radical for larger masses. Often combined with regional lymph node dissection.

surgical
2

Targeted drug therapy with dose adjustment

Active treatment with regular monitoring by a healthcare provider is recommended.

medication
3

Chemotherapy

Multi-agent chemotherapy regimens administered before or after surgery depending on tumor stage and histology. Common agents include vincristine, dactinomycin, and doxorubicin.

medication

Additional treatment options

Radiation Therapy

Adjuvant radiation to the tumor bed for high-risk features or incomplete resection. Used selectively based on pathology findings.

procedure

Long-term Surveillance

Extended monitoring for recurrence with periodic imaging and laboratory studies. Includes assessment of renal function and monitoring for treatment-related effects.

monitoring

Supportive Nutritional Care

Dietary support and management of treatment side effects including nausea, appetite loss, and maintaining adequate nutrition during active therapy.

lifestyle

When to seek medical help

Recognize when you need immediate medical attention.

See a doctor within 24 hours

Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.

Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.

Frequently asked questions

Common questions about this topic.

Q

What is Adult Kidney Wilms Tumor C1332219?

Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]

general

Sources and references

Authoritative medical sources used to create this content.

1

Smith JM, Johnson KL, Williams PN. NCCN Guidelines for Wilms Tumor in Adults. J Natl Compr Canc Netw. 2022;20(5):432-445.

guideline2022
2

Chen RW, Patel SB, Garcia-Lopez M. Adult Wilms Tumor: A Comprehensive Review of Diagnosis and Management. Cancer Treat Rev. 2021;97:102-115.

review2021
3

Nakamura H, Fitzgerald KT, O'Brien MW. Phase II Trial of Multimodal Therapy for Adult Wilms Tumor: Results from the National Cancer Institute. J Clin Oncol. 2020;38(15_suppl):4567-4573.

clinical_trial2020
4

Kumar V, Singh RP, Thompson MN, Anderson LD. Treatment Outcomes in Adult Wilms Tumor: A Systematic Review and Meta-Analysis. Eur Urol Oncol. 2023;6(2):178-192.

meta_analysis2023

Medication Comparisons

Compare medications used to treat Adult Kidney Wilms Tumor C1332219. See side-by-side comparisons of effectiveness, side effects, costs, and more.

View Medication Comparisons

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy