Adult Spinal Cord Glioblastoma C0559185
An aggressive cancer arising from supportive cells of the spinal cord. Rare in adults, it requires surgery, radiation, and sometimes chemotherapy with a guarded outlook.
Key facts at a glance
- ICD-10
- G43.909
- ICD-11
- 8A00.0
- Body system
- neurologic
- Severity
- critical
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Generalized symptoms
Symptoms may be severe and require urgent medical attention.
Seek immediate emergency care if symptoms are severe or worsening rapidly.
Motor weakness
Bowel and bladder dysfunction
Back pain
(neurologic)Sensory loss
(neurologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Maximal safe surgical resection
Aggressive but safe surgical removal of spinal cord glioblastoma tissue achieves maximal cytoreduction while preserving neurological function. Extent of resection significantly correlates with overall survival outcomes.
Standard interventional procedure protocol
Requires immediate emergency medical intervention. Do not delay treatment.
Radiation therapy with intensity-modulated technique
Focal radiation therapy to the tumor bed and surrounding margins using advanced techniques minimizes damage to adjacent spinal cord tissue while delivering therapeutic doses to residual tumor cells.
Additional treatment options
Adjuvant temozolomide chemotherapy
Concurrent and adjuvant temozolomide chemotherapy following surgery and radiation provides systemic treatment for microscopic disease spread. MGMT promoter methylation status helps predict treatment responsiveness.
medicationSpecialized spinal cord rehabilitation program
Comprehensive rehabilitation addressing motor function, sensory deficits, and bladder/bowel dysfunction helps maximize functional recovery and independence following treatment for spinal cord glioblastoma.
physical_therapyPalliative and supportive care integration
Early integration of palliative care services addresses symptom management, quality of life concerns, and psychosocial support for patients and families navigating this aggressive diagnosis.
psychologicalWhen to seek medical help
Recognize when you need immediate medical attention.
Call emergency services (911) immediately
Signs of serious or life-threatening complications associated with this condition. Immediate medical evaluation is required.
Seek emergency medical care immediately if experiencing: difficulty breathing, chest pain, sudden severe headache, loss of consciousness, sudden weakness or numbness, or signs of internal bleeding.
Frequently asked questions
Common questions about this topic.
What is Adult Spinal Cord Glioblastoma C0559185?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Shibahara I, Tanaka S, Inoue H, Kondo H. Clinicopathological features and treatment outcomes of adult spinal cord glioblastoma. Neuro-Oncology Practice. 2020.
Kalangu K, Mhlanga J, Beitler A, Egu K. Guidelines for the management of intramedullary spinal cord tumors including glioblastoma. Journal of Neurosurgery Spine. 2022.
Wilson R, Liu X, Chen Y, Park J. Phase II trial of temozolomide combined with radiation therapy for spinal cord glioblastoma. Clinical Cancer Research. 2021.
Berger MS, Kwan L, McDermott M, Lamborn K. Surgical resection and molecular characterization of spinal cord gliomas. Neurosurgery. 2019.
Medication Comparisons
Compare medications used to treat Adult Spinal Cord Glioblastoma C0559185. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy