Adult Vagina Botryoid Embryonal Rhabdomyosarcoma C1515893
A rare malignant vaginal tumor with a grape-like appearance. Though more common in children, adults can be affected. Treatment typically involves surgery, chemotherapy, and radiation.
Key facts at a glance
- ICD-10
- N50.9
- ICD-11
- GA00.0
- Body system
- reproductive
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Vaginal bleeding
Generalized symptoms
(reproductive)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Vaginal mass protruding from introitus
(reproductive)Pelvic pain
(reproductive)Urinary obstruction causing urinary retention
(reproductive)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Targeted drug therapy with dose adjustment
Active treatment with regular monitoring by a healthcare provider is recommended.
Wide Local Excision
Surgical removal of the tumor with wide margins to achieve complete resection. This is typically combined with reconstructive procedures to maintain vaginal function and appearance.
Multimodal Chemotherapy
Combination chemotherapy regimens, often including vincristine, actinomycin D, and cyclophosphamide (VAC), used to shrink tumors before surgery or eliminate residual disease after resection.
Additional treatment options
Radiation Therapy
External beam radiation therapy targeting the tumor site, typically employed when surgical resection would compromise organ function or in cases of positive margins.
procedureSurveillance Imaging and Tumor Markers
Regular follow-up with pelvic MRI/CT scans and tumor markers such as AFP to detect recurrence early. Typically performed every 3-6 months for the first 2-3 years.
monitoringPsycho-oncology Support
Psychological counseling and support services to address anxiety, depression, body image concerns, and sexual health issues that commonly affect patients undergoing treatment for pelvic cancers.
psychologicalWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Adult Vagina Botryoid Embryonal Rhabdomyosarcoma C1515893?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Hartmann O, Renard N, Delobel A. Botryoid embryonal rhabdomyosarcoma of the female genital tract: A systematic review. Sarcoma Research. 2019.
NCCN Guidelines Panel. Soft Tissue Sarcoma, Version 3.2021. National Comprehensive Cancer Network. 2021.
Ferrari A, Bisogno G, Casanova M. Vaginal rhabdomyosarcoma in adults: A retrospective multicenter study. Pediatric Blood Cancer. 2018.
Hawkins DS, Amdahl BA, Meyer WH. Rhabdomyosarcoma in Adults and Children: Current Treatment Approaches. J Clin Oncol. 2020.
Medication Comparisons
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View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy