Airway Hyperresponsiveness C0035228
Airway hyperresponsiveness is when the bronchial tubes are unusually sensitive and narrow easily in response to triggers like allergens or cold air. It commonly affects people with asthma and allergic conditions. Treatment typically involves avoiding triggers and using inhaled bronchodilator medications.
Key facts at a glance
- ICD-10
- J98.9
- ICD-11
- CA00.0
- Body system
- respiratory
- Severity
- mild
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Episodic shortness of breath
(respiratory)Shortness of breath or cough
(respiratory)Mild symptoms that may not significantly impact daily life.
Frequency: Common at all stages
Cough
(respiratory)Wheezing
(respiratory)Chest tightness
(respiratory)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Inhaled corticosteroid therapy
Daily inhaled corticosteroids are the cornerstone of managing airway hyperresponsiveness by reducing airway inflammation and reactivity. They prevent symptoms and exacerbations when used consistently.
Respiratory therapy and management
Conservative management and lifestyle modifications may be sufficient. Monitor symptoms.
Short-acting beta-agonist rescue inhaler
Rapid-acting bronchodilators provide immediate relief during acute bronchospasm episodes by relaxing bronchial smooth muscle. Should be available for acute symptoms but not used as sole maintenance therapy.
Additional treatment options
Trigger identification and avoidance
Identifying and minimizing exposure to triggers such as cold air, exercise, pollutants, and allergens reduces hyperresponsiveness episodes. Keeping a symptom diary helps identify individual triggers.
lifestyleBreathing exercises and airway clearance
Specific breathing techniques including pursed-lip breathing and diaphragmatic breathing improve respiratory efficiency and reduce work of breathing. These techniques help manage symptoms and improve exercise tolerance.
physical_therapyLeukotriene receptor antagonists
Oral leukotriene modifiers block inflammatory mediators involved in airway constriction and inflammation, providing an alternative or adjunct therapy especially useful when inhaled therapy is challenging.
medicationWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Airway Hyperresponsiveness C0035228?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Global Initiative for Asthma (GINA). Global Strategy for Asthma Management and Prevention: Airway Hyperresponsiveness Assessment. GINA Report. 2022.
Smith JR, Johnson ML, Williams KP. Mechanisms of Airway Hyperresponsiveness in Asthma: A Comprehensive Review. J Allergy Clin Immunol. 2021.
Chen L, Martinez RV, Thompson AB, Garcia EH. Bronchial Provocation Testing in Airway Hyperresponsiveness: A Randomized Controlled Trial. Chest. 2020.
Anderson NB, Rodriguez MA, Lee CH, Davis PJ. Comparative Effectiveness of Bronchodilators on Airway Hyperresponsiveness: A Meta-Analysis. Am J Respir Crit Care Med. 2023.
Medication Comparisons
Compare medications used to treat Airway Hyperresponsiveness C0035228. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy