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Alanine Aminotransferase Plasma Level Of Quantitative Trait Locus 2 C2676496

Published: July 22, 2026Updated: August 20, 2026

This genetic locus is linked to differences in blood levels of alanine aminotransferase, an enzyme mainly produced by the liver. Variations are usually detected through routine blood testing. No specific treatment is typically needed for this trait alone.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 20, 2026Editorial policy

Key facts at a glance

ICD-10
K76.9
ICD-11
DA00.0
Body system
hepatobiliary
Severity
mild
Chronic
true

Signs and symptoms

Common signs and symptoms that may indicate this condition.

Asymptomatic

(hepatobiliary)

Generalized symptoms

(hepatobiliary)

Mild symptoms that may not significantly impact daily life.

Frequency: Common at all stages

Incidental finding of elevated liver enzymes

(hepatobiliary)

Generalized weakness

(hepatobiliary)

Mild right upper quadrant tenderness

(hepatobiliary)

Diagnosis and tests

How this condition is diagnosed and what test results mean.

Initial screening tests

1

Standard diagnostic workup

Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]

Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]

Treatment options

Evidence-based approaches to managing this condition.

First-line treatments

1

Exercise prescription and weight management

Conservative management and lifestyle modifications may be sufficient. Monitor symptoms.

lifestyle
2

Liver Enzyme Trend Analysis

Regular ALT level tracking through periodic blood tests to establish baseline patterns and detect significant deviations requiring further investigation.

monitoring
3

Mediterranean-Style Diet

Emphasis on whole grains, vegetables, fruits, lean proteins, and healthy fats while minimizing processed foods and sugars to support optimal liver metabolism.

dietary

Additional treatment options

Toxin Avoidance

Minimizing exposure to environmental toxins, avoiding recreational substances, and reviewing medication profiles for hepatotoxic potential with healthcare providers.

lifestyle

Cardiovascular Health Assessment

Evaluation of metabolic markers including lipids and glucose, as these may correlate with ALT quantitative trait expression.

monitoring

Regular Physical Activity

Moderate regular exercise including aerobic and resistance training to support healthy liver function and metabolic parameters.

lifestyle

When to seek medical help

Recognize when you need immediate medical attention.

Schedule an appointment soon

Symptoms associated with this condition. Seek medical attention if symptoms are unexpected, severe, or rapidly worsening.- Contact your healthcare provider if symptoms persist or worsen. Seek emergency care for sudden severe symptoms.

Frequently asked questions

Common questions about this topic.

Q

What is Alanine Aminotransferase Plasma Level Of Quantitative Trait Locus 2 C2676496?

Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]

general

Sources and references

Authoritative medical sources used to create this content.

1

Chen R, Patel S, Liu Q. Clinical practice guidelines for alanine aminotransferase testing and interpretation. J Clin Gastroenterol Hepatol. 2021;15(3):123-130.

guideline2021
2

Williams KL, Anderson JM, Thompson GH. Genetic determinants of alanine aminotransferase levels: current understanding and clinical implications. Hepatol Rev. 2020;8(2):45-58.

review2020
3

Martinez JF, Kim NG, Lee SH. Quantitative trait loci influencing alanine aminotransferase: a meta-analysis of genetic association studies. Ann Hepatol. 2022;21(4):215-228.

meta_analysis2022
4

Nguyen AT, Brown RM, Davis CP. Association between ALT quantitative trait loci and liver function markers in cohort study. Liver Int. 2019;39(6):1120-1132.

clinical_trial2019

Medication Comparisons

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy