Alg8 Related Autosomal Dominant Polycystic Kidney And Or Liver Disease Cn379637
An inherited condition causing fluid-filled cysts in kidneys and sometimes the liver. Treatment focuses on managing complications and preserving organ function.
Key facts at a glance
- ICD-10
- Q63.9
- ICD-11
- LA00.0
- Body system
- renal
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Changes in urination or swelling
(renal)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Hypertension
(renal)Flank pain
(renal)Hematuria
(renal)Hepatic cyst formation
(renal)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Multisystem Imaging Surveillance
Regular imaging of kidneys and liver through ultrasound, CT, or MRI to monitor cyst growth and organ function. Blood tests assess kidney and liver function markers periodically to detect changes early.
Renal disease management
Treatment options should be discussed with a qualified healthcare provider.
Blood Pressure Management
Use of antihypertensive medications to control blood pressure and protect kidney function. ACE inhibitors or ARBs are commonly used as they may slow cyst progression and provide renal protection.
Additional treatment options
Cyst Decompression Procedures
Surgical interventions to drain or remove problematic cysts causing pain, bleeding, or organ compression. Options include laparoscopic cyst decortication or more extensive surgical approaches depending on cyst location and severity.
surgicalRenal-Protective Diet
Dietary modifications including reduced sodium intake, moderate protein consumption, and adequate hydration. These changes help manage blood pressure and reduce kidney strain while maintaining nutritional balance.
dietaryActivity and Pain Management
Regular low-impact exercise to maintain cardiovascular health while managing abdominal discomfort. Heat therapy, gentle stretching, and activity pacing help manage symptoms during cyst-related pain episodes.
lifestyleWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Alg8 Related Autosomal Dominant Polycystic Kidney And Or Liver Disease Cn379637?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Cornec-Le Gall E, Audrezet MP, Le Meur Y. Genetics of autosomal dominant polycystic kidney disease: clinical implications. Nephrol Dial Transplant. 2022.
Chapman AB, Devuyst O, Eckardt KU, et al. Autosomal dominant polycystic kidney disease (ADPKD): executive summary from a Kidney Disease: Improving Global Outcomes (KDIGO) controversies conference. Kidney Int. 2015.
Gevers TJ, Drenth JP. Diagnosis and management of polycystic liver disease. Nat Rev Gastroenterol Hepatol. 2013.
Besse W, Dong K, Choi J, et al. Polycystic kidney disease genes: insights from rare variants and population studies. Clin J Am Soc Nephrol. 2021.
Medication Comparisons
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This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy