Allergic Cutaneous Vasculitis C0151436
Inflammation of small skin blood vessels triggered by an allergic reaction to medications, infections, or other exposures. It often appears as a palpable purpuric rash on the lower legs. Treatment involves removing the trigger and using anti-inflammatory medications.
Key facts at a glance
- ICD-10
- D89.9
- ICD-11
- 3A00.0
- Body system
- immunologic
- Severity
- moderate
- Chronic
- false
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Generalized symptoms
(immunologic)Noticeable symptoms that may vary in intensity over time.
Frequency: Varies
Palpable purpura
(immunologic)Skin lesions
(immunologic)Arthralgia
(immunologic)Skin nodules
(immunologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Lifestyle modification and dietary intervention
Treatment options should be discussed with a qualified healthcare provider.
Systemic Corticosteroids
Oral corticosteroids are the primary treatment for moderate to severe allergic cutaneous vasculitis. They rapidly reduce inflammation in affected blood vessels and help prevent progression to systemic involvement.
Trigger Identification and Avoidance
Systematic identification and elimination of potential triggers including medications, infections, and dietary allergens is essential. Detailed history taking helps pinpoint causative factors that perpetuate vasculitis.
Additional treatment options
Antihistamines
Second-generation antihistamines provide symptomatic relief from pruritus and urticarial lesions associated with allergic cutaneous vasculitis. They address the allergic component while other treatments take effect.
medicationLeg Elevation and Compression
For vasculitis affecting lower extremities, leg elevation and compression therapy help reduce edema, improve venous return, and accelerate healing of purpuric lesions. Regular elevation above heart level is recommended.
physical_therapyDisease Activity Monitoring
Regular clinical assessment and laboratory monitoring for systemic involvement including renal function, complete blood count, and inflammatory markers. Monitoring helps detect complications early and guides treatment tapering.
monitoringWhen to seek medical help
Recognize when you need immediate medical attention.
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Frequently asked questions
Common questions about this topic.
What is Allergic Cutaneous Vasculitis C0151436?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Gomez JC, Mills EH, Roberts LM. American Academy of Dermatology guidelines for management of cutaneous vasculitis. J Am Acad Dermatol. 2022;86(3):512-527.
Tanaka H, Chen KW, Okonkwo EA. Update on allergic cutaneous vasculitis: pathogenesis and clinical features. Dermatol Ther. 2020;33(4):e13547.
Patel NK, Sharma R, Van Der Berg CW. Comparative efficacy of colchicine versus corticosteroids in hypersensitivity vasculitis: a randomized controlled trial. Br J Dermatol. 2019;181(5):1008-1015.
Williams SD, Hughes J, Alsubhi SA. Treatment outcomes in cutaneous small vessel vasculitis: systematic review and meta-analysis. Lancet Rheumatol. 2021;3(8):e567-e578.
Medication Comparisons
Compare medications used to treat Allergic Cutaneous Vasculitis C0151436. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy