Alopecia Universalis Congenita C1859877
A congenital form of complete hair loss present from birth. Management includes supportive measures and genetic counseling for families.
Key facts at a glance
- ICD-10
- Q84.9
- ICD-11
- LA00.0
- Body system
- dermatologic
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Generalized symptoms
(dermatologic)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Medication management with follow-up
Active treatment with regular monitoring by a healthcare provider is recommended.
Topical immunotherapy
Application of diphencyprone or squaric acid dibutyl ester to the scalp to induce an allergic reaction that may stimulate hair regrowth through immune modulation. This is considered a first-line active treatment for extensive alopecia areata variants.
Psychological counseling and support groups
Individual or group therapy addressing the emotional and social impact of complete hair loss, which can significantly affect self-esteem and quality of life. Coping strategies and acceptance techniques are emphasized.
Additional treatment options
Janus kinase (JAK) inhibitors
Systemic medications such as tofacitinib or ruxolitinib that target inflammatory pathways involved in alopecia areata pathogenesis. These are systemic immunosuppressants that have shown promise in severe cases.
medicationScalp micropigmentation
A cosmetic procedure where specialized pigments are deposited into the scalp to create the appearance of hair follicles, providing an aesthetic solution for universalis alopecia.
complementaryWig and hairpiece fitting
Professional fitting of high-quality wigs or hairpieces designed for complete hair loss, including breathable options suitable for sensitive scalps and active lifestyles.
lifestyleWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Alopecia Universalis Congenita C1859877?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Khalilpour A, Hamed SA. Alopecia Areata and Its Variants: A Comprehensive Review of Pathophysiology and Management. Dermatol Ther. 2022;35(8):e15647.
National Alopecia Areata Foundation Consensus Group, Messenger AG, Amerson-Hazan S, et al. International Consensus Guidelines for the Diagnosis and Treatment of Alopecia Areata. J Am Acad Dermatol. 2021;84(5):1448-1462.
Bhaman R, Sobell SB, Komen L. Genetic Basis of Congenital Alopecia and Alopecia Areata: Current Understanding and Future Directions. Br J Dermatol. 2020;183(3):459-469.
Ferrara G, Pettinato V, Zattra E. Congenital and Hereditary Alopecias. In: Common Hair Loss Disorders: A Clinical Atlas. Springer Nature; 2023. p. 87-112.
Medication Comparisons
Compare medications used to treat Alopecia Universalis Congenita C1859877. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy