Alport Syndrome 3 Cn380065
A genetic condition affecting kidney function, hearing, and vision due to collagen problems. Treatment focuses on kidney protection and managing symptoms.
Key facts at a glance
- ICD-10
- Q63.9
- ICD-11
- LA00.0
- Body system
- renal
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Changes in urination or swelling
(renal)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Hematuria
(renal)Proteinuria
(renal)Sensorineural hearing loss
(renal)Ocular anomalies
(renal)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
ACE inhibitor therapy
Angiotensin-converting enzyme inhibitors to reduce proteinuria and slow kidney disease progression. Provides renoprotective effects by decreasing intraglomerular pressure.
Renal disease management
Active treatment with regular monitoring by a healthcare provider is recommended.
Renal function surveillance
Regular monitoring of kidney function through estimated glomerular filtration rate, urinalysis, and protein quantification. Allows early detection of disease progression and timely treatment adjustments.
Additional treatment options
Sodium and protein restriction
Dietary modifications to reduce kidney workload, including sodium restriction for blood pressure control and moderate protein intake adjustment based on renal function stage.
dietaryAudiologic monitoring and hearing support
Regular hearing evaluations to detect sensorineural hearing loss associated with Alport syndrome. Hearing aids or other assistive devices may be prescribed when needed.
procedurePsychosocial support and genetic counseling
Psychological support for patients and families dealing with chronic kidney disease and genetic condition implications. Genetic counseling helps families understand inheritance patterns and family planning options.
psychologicalWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Alport Syndrome 3 Cn380065?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Kashtan CE, Ding J, Garosi G, et al. Expert guidelines for the management of Alport syndrome. Kidney Int. 2021.
Gibson J, Fieldhouse R, Chan MM. Narrative review of Alport syndrome genetics and clinical manifestations. Nat Rev Nephrol. 2020.
Gross O, Licht C, Helppi J, et al. Efficacy of renin-angiotensin blockade in Alport syndrome: a prospective clinical trial. J Am Soc Nephrol. 2018.
Nozu K, Nakanishi K, Krol RP, et al. Genetic and clinical aspects of Alport syndrome type III. Clin Exp Nephrol. 2019.
Medication Comparisons
Compare medications used to treat Alport Syndrome 3 Cn380065. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy