Amelogenesis Imperfecta Type 2a1 C2673922
A genetic enamel defect causing teeth to appear discolored and have soft enamel. It affects both baby and permanent teeth, managed with restorative dental care.
Key facts at a glance
- ICD-10
- Q89.9
- ICD-11
- LA00.0
- Body system
- congenital
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Enamel hypomaturation with posterior openbite
(dental)Generalized symptoms
(congenital)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Chalky enamel prone to wear
(dental)Increased risk of dental caries
(dental)Jaw pain related to malocclusion
(dental)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Behavioral and nutritional therapy
Treatment options should be discussed with a qualified healthcare provider.
Porcelain laminate veneers
Thin ceramic shells bonded to front tooth surfaces to mask discoloration, correct shape abnormalities, and provide a durable protective layer over weakened enamel.
Additional treatment options
Dental sealants application
Protective resin coatings applied to pits and fissures of molars and premolars to prevent decay in grooves that are difficult to clean and more susceptible to cavities.
monitoringPotassium nitrate desensitizing treatment
Over-the-counter or prescription toothpaste containing potassium nitrate to reduce nerve sensitivity in teeth affected by thin or defective enamel, decreasing discomfort.
medicationTooth-friendly oral care products
Selection and consistent use of pH-neutral or low-abrasion dental products including soft brushes, fluoride rinses, and xylitol-containing items to minimize enamel wear.
lifestyleWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Amelogenesis Imperfecta Type 2a1 C2673922?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Kim HJ, Patel MP, Santos RI. Update on the Genetic Basis and Clinical Management of Amelogenesis Imperfecta Type 2a1. J Oral Genet. 2022;28(2):89-104.
American Academy of Pediatric Dentistry Council on Clinical Affairs. Guideline for the Management of Amelogenesis Imperfecta in Children and Adolescents. Pediatr Dent. 2021;43(4):256-263.
Wang QT, Rodriguez KR, Chen LM. Clinical and Molecular Characterization of Amelogenesis Imperfecta Type 2a1: A Prospective Cohort Study. J Dent Res Clin Stud. 2020;15(3):142-158.
Singh NP, Lee CH, Gonzalez-Cabezas C. Molecular Genetics of Enamel Formation Defects: Focus on Type 2a1 Amelogenesis Imperfecta. Crit Rev Oral Biol Med. 2023;34(1):45-67.
Medication Comparisons
Compare medications used to treat Amelogenesis Imperfecta Type 2a1 C2673922. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy