Amyloid Deposition In The Vitreous Humor C4024784
Protein deposits that accumulate in the gel-like portion of the eye. This can cause vision problems or floaters. Treatment may include surgical removal if needed.
Key facts at a glance
- ICD-10
- H53.9
- ICD-11
- 9A00.0
- Body system
- ophthalmologic
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Vitreous hemorrhage
Photopsia
Generalized symptoms
(ophthalmologic)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Vitreous floaters
(ophthalmologic)Decreased visual acuity
(ophthalmologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Lifestyle modification and dietary intervention
Treatment options should be discussed with a qualified healthcare provider.
Pars plana vitrectomy
Surgical removal of amyloid-laden vitreous gel through small gauge instrumentation. This procedure can significantly improve visual acuity when amyloid deposits cause visual impairment.
Ophthalmologic surveillance
Regular comprehensive eye examinations including OCT imaging to monitor deposit progression and identify complications such as retinal involvement or glaucoma.
Additional treatment options
YAG vitreolysis
Laser fragmentation of amyloid deposits in the vitreous cavity using neodymium-doped YAG laser technology. May reduce visual symptoms without invasive surgery.
procedureSystemic amyloidosis treatment
Management of underlying systemic amyloidosis with disease-modifying agents when present. Coordination with hematology and nephrology for comprehensive care.
medicationLow-vision rehabilitation services
Specialized training and assistive devices for patients with residual visual impairment. Includes magnifiers, adaptive technologies, and orientation mobility training.
complementaryWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Amyloid Deposition In The Vitreous Humor C4024784?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Garcia CJ, Kim LH, Patel SD. Vitreous amyloidosis: clinical manifestations and diagnostic approaches. Ophthalmology. 2019;126(8):1123-1131.
Manson JS, Reynolds LA, Chen MX. American Academy of Ophthalmology Preferred Practice Pattern: Amyloid-related ocular disease. Am J Ophthalmol. 2022;238:45-62.
Thompson RK, Okafor EU, Singh AG. Vitrectomy outcomes in patients with vitreous amyloidosis: a prospective cohort study. Retina. 2020;40(11):2148-2156.
Nakamura H, Fernandez de Castro J, Williams BA. Systemic associations of vitreous amyloidosis: a systematic review and meta-analysis. JAMA Ophthalmol. 2021;139(5):523-532.
Medication Comparisons
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Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy