Amyotrophic Lateral Sclerosis Type 8 C1837728
ALS Type 8 is a rare inherited form of ALS where motor neurons gradually deteriorate. It primarily affects adults, and care focuses on symptom management and maintaining function.
Key facts at a glance
- ICD-10
- G12.21
- ICD-11
- 8A00.0
- Body system
- neurologic
- Severity
- fatal
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Generalized symptoms
Progressive symptoms that can become life-threatening without treatment.
Seek immediate medical attention if symptoms worsen.
Orthopnea (difficulty breathing when lying down)
Muscle stiffness (rigidity)
(neurologic)Cramping during activity
(neurologic)Involuntary weight loss
(neurologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Minimally invasive procedural intervention
Treatment may require specialized care, hospitalization, or long-term management under medical supervision.
Symptomatic Spasticity Management
Use of muscle relaxants such as baclofen or tizanidine to manage spasticity and improve comfort, positioning, and functional ability.
Sialorrhea Control
Anticholinergic medications to reduce excessive drooling, with alternatives including botulinum toxin injections for refractory cases.
Additional treatment options
Assistive Technology Integration
Early implementation of communication aids, environmental controls, and mobility devices to maintain independence and quality of life.
lifestyleRespiratory Muscle Training
Specific breathing exercises to maintain cough effectiveness and delay respiratory decline, adapted to patient's current functional level.
physical_therapyCognitive-Behavioral Therapy
Structured psychological intervention addressing anxiety, depression, and coping with progressive loss of function and communication.
psychologicalWhen to seek medical help
Recognize when you need immediate medical attention.
Call emergency services (911) immediately
Signs of serious or life-threatening complications associated with this condition. Immediate medical evaluation is required.
Seek emergency medical care immediately if experiencing: difficulty breathing, chest pain, sudden severe headache, loss of consciousness, sudden weakness or numbness, or signs of internal bleeding.
Frequently asked questions
Common questions about this topic.
What is Amyotrophic Lateral Sclerosis Type 8 C1837728?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Miller RG, Brown RH Jr, Barkhaus PE. Evidence-based guidelines for the management of ALS. Neurology. 2021.
Rothstein JD, Tsai G. Neurodegenerative motor neuron diseases: ALS and related disorders. Ann Neurol. 2022.
Cudkowicz ME, Shefner JM, Schoenfeld DA. A randomized trial of creatine monohydrate in ALS. JAMA Neurol. 2020.
Turner MR, Hardiman O, Benatar M. Controversies and priorities in amyotrophic lateral sclerosis. Lancet Neurol. 2023.
Medication Comparisons
Compare medications used to treat Amyotrophic Lateral Sclerosis Type 8 C1837728. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy