Anal Canal Neuroendocrine Neoplasm C1332273
A rare neuroendocrine tumor arising in the anal canal from hormone-producing cells. These tumors can vary in aggressiveness. Treatment typically involves surgery with possible chemotherapy or radiation.
Key facts at a glance
- ICD-10
- K30
- ICD-11
- DA00.0
- Body system
- gastrointestinal
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Abdominal pain
(gastrointestinal)Abdominal pain or nausea
(gastrointestinal)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Flushing
(gastrointestinal)Diarrhea
(gastrointestinal)Bronchospasm
(gastrointestinal)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
GI disease management
Active treatment with regular monitoring by a healthcare provider is recommended.
Surgical Resection
Complete surgical resection of the neuroendocrine tumor with appropriate margins. This is typically performed via transanal excision or more extensive abdominal-perineal resection depending on tumor size and depth.
Additional treatment options
Endoscopic Surveillance
Regular endoscopic monitoring following treatment to detect recurrence. Includes periodic anoscopy, imaging studies, and tumor marker evaluation at defined intervals.
monitoringSomatostatin Analog Therapy
Somatostatin analogs may be considered for symptom control and potential tumor growth inhibition in neuroendocrine tumors, particularly for managing carcinoid-related symptoms.
medicationNutritional Support
Comprehensive nutritional assessment and support to maintain adequate nutrition during and after treatment. Focus on high-protein intake and adequate hydration.
dietaryPsychological Support Services
Counseling and psychological support to address cancer-related anxiety, depression, and body image concerns. Includes referral to support groups and mental health professionals.
psychologicalWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Anal Canal Neuroendocrine Neoplasm C1332273?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Benson AB, Joyrich MP, Bergsland EK, et al. NCCN Guidelines Insights: Neuroendocrine and Adrenal Tumors, Version 2.2021. J Natl Compr Canc Netw. 2021.
Modlin IM, Oberg K, Chung DC, et al. Gastroenteropancreatic neuroendocrine tumours. Lancet Oncol. 2008.
Pape UF, Niederle B, Costa F, et al. ENETS Consensus Guidelines for Neuroendocrine Neoplasms of the Anal Canal and Rectum. Neuroendocrinology. 2016.
Shia J, Guillem JG, Moore HG, et al. Primary neuroendocrine carcinoma of the anal canal. Dis Colon Rectum. 2004.
Medication Comparisons
Compare medications used to treat Anal Canal Neuroendocrine Neoplasm C1332273. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy