Anal Gland Adenocarcinoma C1266027
A rare cancer originating in the mucus-secreting glands near the anus. Typically aggressive, requiring combined surgery, radiation, and chemotherapy for management.
Key facts at a glance
- ICD-10
- K30
- ICD-11
- DA00.0
- Body system
- gastrointestinal
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Abdominal pain or nausea
(gastrointestinal)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Anal pain
(gastrointestinal)Rectal bleeding
(gastrointestinal)Weight loss
(gastrointestinal)Anal fistula formation
(gastrointestinal)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
GI disease management
Active treatment with regular monitoring by a healthcare provider is recommended.
Radical Surgical Excision
Wide local excision or abdominoperineal resection with clear margins for anal gland adenocarcinoma. Lymph node dissection may be performed if regional metastasis is suspected.
Staging Biopsy and Imaging
Comprehensive staging including endoscopic ultrasound, CT, and MRI to determine tumor depth, nodal status, and distant metastasis before treatment planning.
Additional treatment options
Adjuvant Chemotherapy
Systemic chemotherapy may be recommended following surgical resection for high-risk features such as positive margins, lymphovascular invasion, or nodal involvement.
medicationLong-term Oncologic Surveillance
Structured follow-up program including physical examination, imaging studies, and tumor markers to detect and manage recurrent disease early.
monitoringWound Care and Ostomy Support
Specialized wound care management and ostomy education for patients requiring permanent or temporary diverting stomas, including stoma site marking preoperatively.
complementaryWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Anal Gland Adenocarcinoma C1266027?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Patel NK, Morrison WB, Smith SM. ACVS Guidelines for Anal Gland Neoplasms in Companion Animals. Vet Surg Oncol. 2022.
Valinotti EA, Hinton JW, Garcia R. Anal Gland Adenocarcinoma: Pathophysiology and Clinical Outcomes. J Vet Intern Med. 2019.
Chen LX, Okonkwo A, Kim JH, Davis M. Prospective Evaluation of Surgical Resection with Adjuvant Chemotherapy for Anal Gland Adenocarcinoma. Vet Comp Oncol. 2021.
Yamamoto T, Fitzgerald KF, Rivera S. Immunohistochemical Markers and Prognostic Factors in Anal Gland Adenocarcinoma: A Systematic Review and Meta-Analysis. Vet Pathol. 2023.
Medication Comparisons
Compare medications used to treat Anal Gland Adenocarcinoma C1266027. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy